Dong S. Lee

Daejeon, Republic of Korea

Last Updated: 09/26/2026

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Found 10 publications

De novo and scaffold-based design of GDF15 binders for cancer cachexia diagnostics and therapeutics.

De novo and scaffold-based design of GDF15 binders for cancer cachexia diagnostics and therapeutics.

Journal: Experimental & molecular medicine

Published: September 24, 2025

Autism-associated MDGA1 missense mutations impair distinct facets of central nervous system development.

Autism-associated MDGA1 missense mutations impair distinct facets of central nervous system development.

Journal: medRxiv : the preprint server for health sciences

Published: June 30, 2025

Bazedoxifene reverses sexually dimorphic autistic-like abnormalities in biallelic MDGA1-mutant mice.

Bazedoxifene reverses sexually dimorphic autistic-like abnormalities in biallelic MDGA1-mutant mice.

Journal: EMBO molecular medicine

Published: June 09, 2025

Structural insight into TLR4/MD-2 activation by synthetic LPS mimetics with distinct binding modes.

Structural insight into TLR4/MD-2 activation by synthetic LPS mimetics with distinct binding modes.

Journal: Nature communications

Published: October 23, 2024

De novo design of protein minibinder agonists of TLR3.

De novo design of protein minibinder agonists of TLR3.

Journal: bioRxiv : the preprint server for biology

Published: April 25, 2024

De novo design of protein minibinder agonists of TLR3.

De novo design of protein minibinder agonists of TLR3.

Journal: Nature communications

Published: April 18, 2024

Crystal structure of LRG1 and the functional significance of LRG1 glycan for LPHN2 activation.

Crystal structure of LRG1 and the functional significance of LRG1 glycan for LPHN2 activation.

Journal: Experimental & molecular medicine

Published: November 26, 2022

Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex.

Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex.

Journal: Nature communications

Published: March 01, 2022

PD-L1-directed PlGF/VEGF blockade synergizes with chemotherapy by targeting CD141+ cancer-associated fibroblasts in pancreatic cancer.

PD-L1-directed PlGF/VEGF blockade synergizes with chemotherapy by targeting CD141+ cancer-associated fibroblasts in pancreatic cancer.

Journal: Nature communications

Published: November 23, 2021

Latrophilin-2 is a novel receptor of LRG1 that rescues vascular and neurological abnormalities and restores diabetic erectile function.

Latrophilin-2 is a novel receptor of LRG1 that rescues vascular and neurological abnormalities and restores diabetic erectile function.

Journal: Experimental & molecular medicine

Published: November 02, 2021

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Last Updated: 09/26/2026