Dong Y. Guo

No. 516 Jungong Road
Shanghai, 200093, China

Last Updated: 09/26/2026

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Found 101 publications

p38 MAP kinase senses short-chain fatty acids to attenuate Toll-like receptor signaling and intestinal inflammation.

p38 MAP kinase senses short-chain fatty acids to attenuate Toll-like receptor signaling and intestinal inflammation.

Journal: Science advances
Published: July 10, 2026

Discovery of a Novel Potent and Orally Efficacious PGK1 Inhibitor C67-47 for the Treatment of Human Pancreatic Cancer.

Discovery of a Novel Potent and Orally Efficacious PGK1 Inhibitor C67-47 for the Treatment of Human Pancreatic Cancer.

Journal: Journal of medicinal chemistry
Published: May 29, 2026

Structure-Guided Engineering of UGT94B1M0 Enhances Thermostability and Enables Efficient Rebaudioside D Biosynthesis via Coupled UDP-Glucose Regeneration.

Structure-Guided Engineering of UGT94B1M0 Enhances Thermostability and Enables Efficient Rebaudioside D Biosynthesis via Coupled UDP-Glucose Regeneration.

Journal: Journal of agricultural and food chemistry
Published: May 07, 2026

Photochemical Alkylation of Heterocycles Enabled by Oxalic Dianion as Traceless Electron Donor.

Photochemical Alkylation of Heterocycles Enabled by Oxalic Dianion as Traceless Electron Donor.

Journal: Organic letters
Published: April 07, 2026

Author Correction: Structural insights into antagonist recognition by the vasopressin V2 receptor.

Author Correction: Structural insights into antagonist recognition by the vasopressin V2 receptor.

Journal: Nature communications
Published: March 24, 2026

Development of 2,8-diazaspiro[4.5]decan-3-ones as novel sigma-1 receptor antagonists and evaluation of antihyperalgesic effects.

Development of 2,8-diazaspiro[4.5]decan-3-ones as novel sigma-1 receptor antagonists and evaluation of antihyperalgesic effects.

Journal: Bioorganic chemistry
Published: January 21, 2026

Understanding drug-target residence time and the implications on drug discovery.

Understanding drug-target residence time and the implications on drug discovery.

Journal: Expert opinion on drug discovery
Published: January 21, 2026

Discovery of Non-benzoazacyclic V2R Antagonists for the Treatment of Autosomal Dominant Polycystic Kidney Disease.

Discovery of Non-benzoazacyclic V2R Antagonists for the Treatment of Autosomal Dominant Polycystic Kidney Disease.

Journal: Journal of medicinal chemistry
Published: November 29, 2025

Podocyte mPGES-2 Determines Renal Aging and Contributes to Senile Osteoporosis.

Podocyte mPGES-2 Determines Renal Aging and Contributes to Senile Osteoporosis.

Journal: Aging cell
Published: November 06, 2025

UBE2C-PI3K/AKT-mediated upregulation of MTHFD2 promotes tumor progression in hepatocellular carcinoma.

UBE2C-PI3K/AKT-mediated upregulation of MTHFD2 promotes tumor progression in hepatocellular carcinoma.

Journal: International immunopharmacology
Published: September 24, 2025

De Novo Discovery of a Macrocyclic Peptide Antagonist of Interleukin-11 with Antirenal Fibrotic Efficacy.

De Novo Discovery of a Macrocyclic Peptide Antagonist of Interleukin-11 with Antirenal Fibrotic Efficacy.

Journal: Journal of medicinal chemistry
Published: September 18, 2025

Targeting USP28 inhibits clear cell renal cell carcinoma growth.

Targeting USP28 inhibits clear cell renal cell carcinoma growth.

Journal: Cellular signalling
Published: August 15, 2025
Showing 1-12 of 101

Last Updated: 09/26/2026