Dongliang Guan

No. 19A Yuquan Road
Yuquan, 100049, China

Last Updated: 09/26/2026

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Found 16 publications

Discovery of New Teraryl γ-Lactam Derivatives as Potent Antibacterial Agents In Vitro and In Vivo through Dual Cell Wall-Membrane Inhibitions.

Discovery of New Teraryl γ-Lactam Derivatives as Potent Antibacterial Agents In Vitro and In Vivo through Dual Cell Wall-Membrane Inhibitions.

Journal: Journal of medicinal chemistry

Published: April 15, 2026

Amphiphilic Zwitterionic Polymers Induce Liposome Morphogenesis into Nanodiscs for Deep Glioblastoma Infiltration.

Amphiphilic Zwitterionic Polymers Induce Liposome Morphogenesis into Nanodiscs for Deep Glioblastoma Infiltration.

Journal: Angewandte Chemie (International ed. in English)

Published: December 03, 2025

Novel Vancomycin-β-Lactam Hybrids: Structure-Activity Relationships and Therapeutic Potential Against VISA and VRE.

Novel Vancomycin-β-Lactam Hybrids: Structure-Activity Relationships and Therapeutic Potential Against VISA and VRE.

Journal: ChemMedChem

Published: November 26, 2025

A Broad-Spectrum Abietane Diterpenoid Derivative that Targets Lipid II Cycle and Bacterial Membrane to Combat Multidrug Resistance.

A Broad-Spectrum Abietane Diterpenoid Derivative that Targets Lipid II Cycle and Bacterial Membrane to Combat Multidrug Resistance.

Journal: Journal of medicinal chemistry

Published: September 25, 2025

Novel Rationally Designed Lipopeptides Derived from Bacitracin: Combating Multidrug Resistance and Evading Bacitracin Resistance via Potentiated Cell Wall and Membrane Inhibitions.

Novel Rationally Designed Lipopeptides Derived from Bacitracin: Combating Multidrug Resistance and Evading Bacitracin Resistance via Potentiated Cell Wall and Membrane Inhibitions.

Journal: Journal of medicinal chemistry

Published: August 01, 2025

Novel Aryl Sulfonium Modification on Vancomycin to Tackle MRSA and VRE In Vitro and In Vivo through Dual Enhanced Cell-Wall and Membrane Inhibition.

Novel Aryl Sulfonium Modification on Vancomycin to Tackle MRSA and VRE In Vitro and In Vivo through Dual Enhanced Cell-Wall and Membrane Inhibition.

Journal: Journal of medicinal chemistry

Published: April 12, 2025

Single Amine or Guanidine Modification on Norvancomycin and Vancomycin to Overcome Multidrug-Resistance through Augmented Lipid II Binding and Increased Membrane Activity.

Single Amine or Guanidine Modification on Norvancomycin and Vancomycin to Overcome Multidrug-Resistance through Augmented Lipid II Binding and Increased Membrane Activity.

Journal: Journal of medicinal chemistry

Published: November 06, 2024

A Vancomycin-Templated DNA-Encoded Library for Combating Drug-Resistant Bacteria.

A Vancomycin-Templated DNA-Encoded Library for Combating Drug-Resistant Bacteria.

Journal: Journal of medicinal chemistry

Published: March 14, 2024

Carbohydrate Strengthens the Immunotherapeutic Effect of Small-Molecule PD-L1 Inhibitors.

Carbohydrate Strengthens the Immunotherapeutic Effect of Small-Molecule PD-L1 Inhibitors.

Journal: Journal of medicinal chemistry

Published: May 25, 2023

A facile and selective derivatization approach on kynurenine-NH2 in daptomycin, leading to the discovery of hexakynomycin to combat multidrug-resistant Gram-positive pathogens especially daptomycin-resistant bacteria.

A facile and selective derivatization approach on kynurenine-NH2 in daptomycin, leading to the discovery of hexakynomycin to combat multidrug-resistant Gram-positive pathogens especially daptomycin-resistant bacteria.

Journal: European journal of medicinal chemistry

Published: May 15, 2023

Single Modification at the N-Terminus of Norvancomycin to Combat Drug-Resistant Gram-Positive Bacteria.

Single Modification at the N-Terminus of Norvancomycin to Combat Drug-Resistant Gram-Positive Bacteria.

Journal: ChemMedChem

Published: December 29, 2022

Total and Semisyntheses of Polymyxin Analogues with 2-Thr or 10-Thr Modifications to Decipher the Structure-Activity Relationship and Improve the Antibacterial Activity.

Total and Semisyntheses of Polymyxin Analogues with 2-Thr or 10-Thr Modifications to Decipher the Structure-Activity Relationship and Improve the Antibacterial Activity.

Journal: Journal of medicinal chemistry

Published: April 28, 2021

Showing 1-12 of 16

Last Updated: 09/26/2026