Dongting Zhangsun

Guangxi Key Laboratory Of Special Biomedicine
Nanning, 530004, China

Last Updated: 09/26/2026

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Found 97 publications

Rational Redesign of an α-Helical Marine Toxin Scaffold Enables a Safe and Broad-Spectrum Anti-ESKAPE Lipopeptide.

Rational Redesign of an α-Helical Marine Toxin Scaffold Enables a Safe and Broad-Spectrum Anti-ESKAPE Lipopeptide.

Journal: Journal of medicinal chemistry

Published: May 28, 2026

Trihexyphenidyl Ameliorates Depression-like Behaviors in Adult Zebrafish Exposed to Chronic Unpredictable Stress, Consistent with Regulation of the MAPK Signaling Pathway.

Trihexyphenidyl Ameliorates Depression-like Behaviors in Adult Zebrafish Exposed to Chronic Unpredictable Stress, Consistent with Regulation of the MAPK Signaling Pathway.

Journal: Biomolecules

Published: March 31, 2026

Design and engineering of μO-conotoxin MfVIA mutants to enhance NaV1.8 inhibition and analgesic efficacy in inflammatory pain.

Design and engineering of μO-conotoxin MfVIA mutants to enhance NaV1.8 inhibition and analgesic efficacy in inflammatory pain.

Journal: Bioorganic & medicinal chemistry

Published: March 05, 2026

LvID-BDP: A Conotoxin-Based Fluorescent Probe for Visualizing α7 nAChR Expression in Intestinal Inflammation.

LvID-BDP: A Conotoxin-Based Fluorescent Probe for Visualizing α7 nAChR Expression in Intestinal Inflammation.

Journal: Journal of medicinal chemistry

Published: February 24, 2026

Identification of key determinants in α subunit for α-conotoxin [D1G, ΔQ14]LvIC selectively targeting rat α6/α3β4 nicotinic acetylcholine receptor.

Identification of key determinants in α subunit for α-conotoxin [D1G, ΔQ14]LvIC selectively targeting rat α6/α3β4 nicotinic acetylcholine receptor.

Journal: Neuropharmacology

Published: February 09, 2026

Single amino acid substitutions modulate the function of α9α10 nicotinic acetylcholine receptor.

Single amino acid substitutions modulate the function of α9α10 nicotinic acetylcholine receptor.

Journal: International journal of biological macromolecules

Published: January 12, 2026

Rational β-turn engineering of a disulfide-free β-hairpin-like antimicrobial peptide W2PG with enhanced stability, selectivity, and in vivo efficacy.

Rational β-turn engineering of a disulfide-free β-hairpin-like antimicrobial peptide W2PG with enhanced stability, selectivity, and in vivo efficacy.

Journal: Bioorganic chemistry

Published: December 22, 2025

Transcriptome-guided discovery and active-site gatekeeper engineering of a Viola arcuata asparaginyl ligase with superior catalytic performance.

Transcriptome-guided discovery and active-site gatekeeper engineering of a Viola arcuata asparaginyl ligase with superior catalytic performance.

Journal: The Journal of biological chemistry

Published: December 03, 2025

Functional diversification of Viola arcuata protein disulfide isomerases and their roles in cyclotide oxidative folding.

Functional diversification of Viola arcuata protein disulfide isomerases and their roles in cyclotide oxidative folding.

Journal: International journal of biological macromolecules

Published: November 29, 2025

Efficient hydrazide-mediated total synthesis of Möbius cyclotides from Viola japonica and elucidation of the antibacterial mechanism of Vija 31.

Efficient hydrazide-mediated total synthesis of Möbius cyclotides from Viola japonica and elucidation of the antibacterial mechanism of Vija 31.

Journal: Biochemical and biophysical research communications

Published: November 24, 2025

Hippocampal Metabolomics Reveal the Mechanism of α-Conotoxin [S9K]TxID Attenuating Nicotine Addiction.

Hippocampal Metabolomics Reveal the Mechanism of α-Conotoxin [S9K]TxID Attenuating Nicotine Addiction.

Journal: Marine drugs

Published: November 05, 2025

α-Conotoxin LvID, an antagonist of α7 nicotinic acetylcholine receptor, mitigates Alzheimer-associated phenotypes by inhibiting Aβ deposition and reactive astrogliosis.

α-Conotoxin LvID, an antagonist of α7 nicotinic acetylcholine receptor, mitigates Alzheimer-associated phenotypes by inhibiting Aβ deposition and reactive astrogliosis.

Journal: International journal of biological macromolecules

Published: October 24, 2025

Showing 1-12 of 97

Last Updated: 09/26/2026