Dongyin Chen

101 Longmian Avenue
Nanjing, 211166, China

Last Updated: 09/26/2026

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Found 21 publications

Sodium ion channels as therapeutic targets in epilepsy: a drug discovery perspective.

Sodium ion channels as therapeutic targets in epilepsy: a drug discovery perspective.

Journal: Bioorganic chemistry

Published: April 11, 2026

Drug discovery targeting protein arginine methyltransferase 5 (PRMT5): an update.

Drug discovery targeting protein arginine methyltransferase 5 (PRMT5): an update.

Journal: Bioorganic & medicinal chemistry

Published: March 27, 2025

Proof of concept study for developing 1-thienyl-β-carboline derivatives as IDO1 and TDO dual inhibitors to treat Parkinson's disease complicating depression.

Proof of concept study for developing 1-thienyl-β-carboline derivatives as IDO1 and TDO dual inhibitors to treat Parkinson's disease complicating depression.

Journal: European journal of medicinal chemistry

Published: January 10, 2025

Sulforaphane potentiates the efficacy of chemoradiotherapy in glioblastoma by selectively targeting thioredoxin reductase 1.

Sulforaphane potentiates the efficacy of chemoradiotherapy in glioblastoma by selectively targeting thioredoxin reductase 1.

Journal: Cancer letters

Published: August 19, 2024

Phosphorylated protein chip combined with artificial intelligence tools for precise drug screening.

Phosphorylated protein chip combined with artificial intelligence tools for precise drug screening.

Journal: Journal of biomedical research

Published: May 27, 2024

Synthesis and Bioevaluation of 3-(Arylmethylene)indole Derivatives: Discovery of a Novel ALK Modulator with Antiglioblastoma Activities.

Synthesis and Bioevaluation of 3-(Arylmethylene)indole Derivatives: Discovery of a Novel ALK Modulator with Antiglioblastoma Activities.

Journal: Journal of medicinal chemistry

Published: October 20, 2023

Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation.

Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation.

Journal: Cell reports

Published: March 24, 2023

Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas.

Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas.

Journal: Molecular cell

Published: December 02, 2022

Hypoxanthine phosphoribosyl transferase 1 metabolizes temozolomide to activate AMPK for driving chemoresistance of glioblastomas.

Hypoxanthine phosphoribosyl transferase 1 metabolizes temozolomide to activate AMPK for driving chemoresistance of glioblastomas.

Journal: Nature communications

Published: November 02, 2022

Discovery of cysteine-targeting covalent histone methyltransferase inhibitors.

Discovery of cysteine-targeting covalent histone methyltransferase inhibitors.

Journal: European journal of medicinal chemistry

Published: September 12, 2022

Discovery of 1-(Hetero)aryl-β-carboline Derivatives as IDO1/TDO Dual Inhibitors with Antidepressant Activity.

Discovery of 1-(Hetero)aryl-β-carboline Derivatives as IDO1/TDO Dual Inhibitors with Antidepressant Activity.

Journal: Journal of medicinal chemistry

Published: August 08, 2022

JP1 normalizes tumor vasculature to suppress metastasis and facilitate drug delivery by inhibiting IL-8.

JP1 normalizes tumor vasculature to suppress metastasis and facilitate drug delivery by inhibiting IL-8.

Journal: JCI insight

Published: May 09, 2022

Showing 1-12 of 21

Last Updated: 09/26/2026