Doriano Lamba

Rome, 00136, Italy

Last Updated: 09/26/2026

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Found 37 publications

Unveiling the Solvent Effect: DMSO Interaction with Human Nerve Growth Factor and Its Implications for Drug Discovery.

Unveiling the Solvent Effect: DMSO Interaction with Human Nerve Growth Factor and Its Implications for Drug Discovery.

Journal: Molecules (Basel, Switzerland)

Published: June 09, 2025

Preface. Special Issue 14th International Meeting on Cholinesterases and 8th Conference of Paraoxonases: Structure, function and diseases, interactions with organophosphorus and targeted drugs.

Preface. Special Issue 14th International Meeting on Cholinesterases and 8th Conference of Paraoxonases: Structure, function and diseases, interactions with organophosphorus and targeted drugs.

Journal: Chemico-biological interactions

Published: June 15, 2024

Disentangling the formation, mechanism, and evolvement of the covalent methanesulfonyl fluoride acetylcholinesterase adduct: Insights into an aged-like inactive complex susceptible to reactivation by a combination of nucleophiles.

Disentangling the formation, mechanism, and evolvement of the covalent methanesulfonyl fluoride acetylcholinesterase adduct: Insights into an aged-like inactive complex susceptible to reactivation by a combination of nucleophiles.

Journal: Protein science : a publication of the Protein Society

Published: October 09, 2023

The NGF R100W Mutation, Associated with Hereditary Sensory Autonomic Neuropathy Type V, Specifically Affects the Binding Energetic Landscapes of NGF and of Its Precursor proNGF and p75NTR.

The NGF R100W Mutation, Associated with Hereditary Sensory Autonomic Neuropathy Type V, Specifically Affects the Binding Energetic Landscapes of NGF and of Its Precursor proNGF and p75NTR.

Journal: Biology

Published: January 13, 2023

Distinct conformational changes occur within the intrinsically unstructured pro-domain of pro-Nerve Growth Factor in the presence of ATP and Mg2.

Distinct conformational changes occur within the intrinsically unstructured pro-domain of pro-Nerve Growth Factor in the presence of ATP and Mg2.

Journal: Protein science : a publication of the Protein Society

Published: September 21, 2022

Kinetic and structural studies on the inhibition of acetylcholinesterase and butyrylcholinesterase by a series of multitarget-directed galantamine-peptide derivatives.

Kinetic and structural studies on the inhibition of acetylcholinesterase and butyrylcholinesterase by a series of multitarget-directed galantamine-peptide derivatives.

Journal: Chemico-biological interactions

Published: May 26, 2022

Untangling the Conformational Plasticity of V66M Human proBDNF Polymorphism as a Modifier of Psychiatric Disorder Susceptibility.

Untangling the Conformational Plasticity of V66M Human proBDNF Polymorphism as a Modifier of Psychiatric Disorder Susceptibility.

Journal: International journal of molecular sciences

Published: May 06, 2022

Kinetic Modeling of Time-Dependent Enzyme Inhibition by Pre-Steady-State Analysis of Progress Curves: The Case Study of the Anti-Alzheimer's Drug Galantamine.

Kinetic Modeling of Time-Dependent Enzyme Inhibition by Pre-Steady-State Analysis of Progress Curves: The Case Study of the Anti-Alzheimer's Drug Galantamine.

Journal: International journal of molecular sciences

Published: April 14, 2022

Small Endogenous Ligands Modulation of Nerve Growth Factor Bioactivity: A Structural Biology Overview.

Small Endogenous Ligands Modulation of Nerve Growth Factor Bioactivity: A Structural Biology Overview.

Journal: Cells

Published: November 05, 2021

A combined evolutionary and structural approach to disclose the primary structural determinants essential for proneurotrophins biological functions.

A combined evolutionary and structural approach to disclose the primary structural determinants essential for proneurotrophins biological functions.

Journal: Computational and structural biotechnology journal

Published: March 05, 2021

Endogenous modulators of neurotrophin signaling: Landscape of the transient ATP-NGF interactions.

Endogenous modulators of neurotrophin signaling: Landscape of the transient ATP-NGF interactions.

Journal: Computational and structural biotechnology journal

Published: February 23, 2021

Peptide-Protein Interactions: From Drug Design to Supramolecular Biomaterials.

Peptide-Protein Interactions: From Drug Design to Supramolecular Biomaterials.

Journal: Molecules (Basel, Switzerland)

Published: January 21, 2021

Showing 1-12 of 37

Last Updated: 09/26/2026