Dorothy C. Wai

Parkville, VIC 3052, Australia

Last Updated: 09/26/2026

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Found 21 publications

Lipidation of the KV1.3 blocking peptide HsTX1[R14A] alters its pharmacokinetics and biodistribution.

Lipidation of the KV1.3 blocking peptide HsTX1[R14A] alters its pharmacokinetics and biodistribution.

Journal: International journal of pharmaceutics

Published: March 25, 2026

Cell-penetrant peptides as novel inhibitors of the interaction of coatomer protein COPB2/RACK2 with protein kinase Cε and cargo proteins.

Cell-penetrant peptides as novel inhibitors of the interaction of coatomer protein COPB2/RACK2 with protein kinase Cε and cargo proteins.

Journal: Biochimica et biophysica acta. Molecular cell research

Published: June 09, 2025

Structure and functional studies of Avt1, a novel peptide from the sea anemone Aulactinia veratra.

Structure and functional studies of Avt1, a novel peptide from the sea anemone Aulactinia veratra.

Journal: Biochimica et biophysica acta. Proteins and proteomics

Published: July 31, 2024

Fragment-based and structure-guided discovery of perforin inhibitors.

Fragment-based and structure-guided discovery of perforin inhibitors.

Journal: European journal of medicinal chemistry

Published: August 01, 2023

Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni.

Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni.

Journal: Biochimica et biophysica acta. Proteins and proteomics

Published: May 09, 2023

Structure-function relationships in ShKT domain peptides: ShKT-Ts1 from the sea anemone Telmatactis stephensoni.

Structure-function relationships in ShKT domain peptides: ShKT-Ts1 from the sea anemone Telmatactis stephensoni.

Journal: Proteins

Published: May 07, 2023

Peripheral Administration of the Kv1.3-Blocking Peptide HsTX1[R14A] Improves Cognitive Performance in Senescence Accelerated SAMP8 Mice.

Peripheral Administration of the Kv1.3-Blocking Peptide HsTX1[R14A] Improves Cognitive Performance in Senescence Accelerated SAMP8 Mice.

Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Published: April 24, 2023

Genomic, functional and structural analyses elucidate evolutionary innovation within the sea anemone 8 toxin family.

Genomic, functional and structural analyses elucidate evolutionary innovation within the sea anemone 8 toxin family.

Journal: BMC biology

Published: January 08, 2023

A Fluorescent Peptide Toxin for Selective Visualization of the Voltage-Gated Potassium Channel KV1.3.

A Fluorescent Peptide Toxin for Selective Visualization of the Voltage-Gated Potassium Channel KV1.3.

Journal: Bioconjugate chemistry

Published: November 04, 2022

A Biodistribution Study of the Radiolabeled Kv1.3-Blocking Peptide DOTA-HsTX1[R14A] Demonstrates Brain Uptake in a Mouse Model of Neuroinflammation.

A Biodistribution Study of the Radiolabeled Kv1.3-Blocking Peptide DOTA-HsTX1[R14A] Demonstrates Brain Uptake in a Mouse Model of Neuroinflammation.

Journal: Molecular pharmaceutics

Published: November 04, 2022

Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone.

Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone.

Journal: Biomolecules

Published: September 27, 2021

Blockade of Microglial Kv1.3 Potassium Channels by the Peptide HsTX1[R14A] Attenuates Lipopolysaccharide-mediated Neuroinflammation.

Blockade of Microglial Kv1.3 Potassium Channels by the Peptide HsTX1[R14A] Attenuates Lipopolysaccharide-mediated Neuroinflammation.

Journal: Journal of pharmaceutical sciences

Published: August 31, 2021

Showing 1-12 of 21

Last Updated: 09/26/2026