Douglas L. Huseby
Uppsala, C 75123, Sweden
Last Updated: 09/26/2026
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Found 33 publications
The Evolutionary Maintenance of Amino Acid Prototrophy in Escherichia coli.
Journal: Genome biology and evolution
Published: August 14, 2026
The COMBINE pneumonia model: a multicenter study to standardize a mouse pneumonia model with Pseudomonas aeruginosa and Klebsiella pneumoniae for antibiotic development.
Journal: Microbiology spectrum
Published: January 14, 2026
Integrated conjugative elements drive the formation of pandemic clones of Escherichia coli with hybrid chromosomes.
Journal: Molecular biology and evolution
Published: December 08, 2025
Impact of early-life human microbiota on the murine host metabolome: insights from a two-generation HMA mouse model and implications for allergic disease.
Journal: BMC microbiology
Published: February 24, 2025
Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: April 05, 2024
Apramycin efficacy against carbapenem- and aminoglycoside-resistant Escherichia coli and Klebsiella pneumoniae in murine bloodstream infection models.
Journal: International journal of antimicrobial agents
Published: June 02, 2023
New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus.
Journal: Journal of medicinal chemistry
Published: March 06, 2023
Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa.
Journal: Journal of medicinal chemistry
Published: January 12, 2023
Evolution of Bacterial Interspecies Hybrids with Enlarged Chromosomes.
Journal: Genome biology and evolution
Published: August 31, 2022
Positive Selection during Niche Adaptation Results in Large-Scale and Irreversible Rearrangement of Chromosomal Gene Order in Bacteria.
Journal: Molecular biology and evolution
Published: March 29, 2022
Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis.
Journal: EBioMedicine
Published: June 23, 2021
Evaluating the potential efficacy and limitations of a phage for joint antibiotic and phage therapy of Staphylococcus aureus infections.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: March 02, 2021
Last Updated: 09/26/2026