Douglas W. Allan

2350 Health Sciences Mall, V6T 1Z3
Vancouver, BC, Canada

Last Updated: 09/26/2026

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Found 27 publications

Context-dependent toxicity of human tau isoforms in a Drosophila tauopathy model.

Context-dependent toxicity of human tau isoforms in a Drosophila tauopathy model.

Journal: Biology open
Published: April 21, 2026

Drosophila wing is a high-throughput and versatile screening tool for Tau-mediated disease mechanisms and drug discovery.

Drosophila wing is a high-throughput and versatile screening tool for Tau-mediated disease mechanisms and drug discovery.

Journal: Disease models & mechanisms
Published: May 20, 2025

Revealing function-altering MECP2 mutations in individuals with autism spectrum disorder using yeast and Drosophila.

Revealing function-altering MECP2 mutations in individuals with autism spectrum disorder using yeast and Drosophila.

Journal: Genetics
Published: April 08, 2025

Functional analysis of human EED variants using Drosophila.

Functional analysis of human EED variants using Drosophila.

Journal: Genetics
Published: May 03, 2024

Adult expression of the cell adhesion protein Fasciclin 3 is required for the maintenance of adult olfactory interneurons.

Adult expression of the cell adhesion protein Fasciclin 3 is required for the maintenance of adult olfactory interneurons.

Journal: Journal of cell science
Published: October 30, 2023

Adult expression of Semaphorins and Plexins is essential for motor neuron survival.

Adult expression of Semaphorins and Plexins is essential for motor neuron survival.

Journal: Scientific reports
Published: February 02, 2023

Dichotomous cis-regulatory motifs mediate the maturation of the neuromuscular junction by retrograde BMP signaling.

Dichotomous cis-regulatory motifs mediate the maturation of the neuromuscular junction by retrograde BMP signaling.

Journal: Nucleic acids research
Published: February 12, 2022

The Hinge Region of the Israeli Acute Paralysis Virus Internal Ribosome Entry Site Directs Ribosomal Positioning, Translational Activity, and Virus Infection.

The Hinge Region of the Israeli Acute Paralysis Virus Internal Ribosome Entry Site Directs Ribosomal Positioning, Translational Activity, and Virus Infection.

Journal: Journal of virology
Published: January 12, 2022

A scalable Drosophila assay for clinical interpretation of human PTEN variants in suppression of PI3K/AKT induced cellular proliferation.

A scalable Drosophila assay for clinical interpretation of human PTEN variants in suppression of PI3K/AKT induced cellular proliferation.

Journal: PLoS genetics
Published: March 30, 2021

A low affinity cis-regulatory BMP response element restricts target gene activation to subsets of Drosophila neurons.

A low affinity cis-regulatory BMP response element restricts target gene activation to subsets of Drosophila neurons.

Journal: eLife
Published: June 03, 2020

Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction.

Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction.

Journal: Nature communications
Published: October 09, 2019

IRES-dependent ribosome repositioning directs translation of a +1 overlapping ORF that enhances viral infection.

IRES-dependent ribosome repositioning directs translation of a +1 overlapping ORF that enhances viral infection.

Journal: Nucleic acids research
Published: July 09, 2018
Showing 1-12 of 27

Last Updated: 09/26/2026