Dounia Le Guillou

Rennes, 35000, France

Last Updated: 09/26/2026

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Found 17 publications

iPSC-Derived Hepatocytes from Patients with MASLD Exhibit Early Mitochondrial Dysfunction.

iPSC-Derived Hepatocytes from Patients with MASLD Exhibit Early Mitochondrial Dysfunction.

Journal: bioRxiv : the preprint server for biology

Published: September 05, 2025

Induced pluripotent stem cell-derived hepatocytes from patients with MASLD exhibit early mitochondrial dysfunction.

Induced pluripotent stem cell-derived hepatocytes from patients with MASLD exhibit early mitochondrial dysfunction.

Journal: Cellular and molecular gastroenterology and hepatology

Published: September 04, 2025

Predicting metabolic dysfunction-associated steatotic liver disease risk using patient-derived induced pluripotent stem cells.

Predicting metabolic dysfunction-associated steatotic liver disease risk using patient-derived induced pluripotent stem cells.

Journal: Stem cells translational medicine

Published: July 15, 2025

Predicting Metabolic Dysfunction Associated Steatotic Liver Disease Risk Using Patient-Derived Induced Pluripotent Stem Cells.

Predicting Metabolic Dysfunction Associated Steatotic Liver Disease Risk Using Patient-Derived Induced Pluripotent Stem Cells.

Journal: bioRxiv : the preprint server for biology

Published: January 27, 2025

Cellular stress in the pathogenesis of nonalcoholic steatohepatitis and liver fibrosis.

Cellular stress in the pathogenesis of nonalcoholic steatohepatitis and liver fibrosis.

Journal: Nature reviews. Gastroenterology & hepatology

Published: July 26, 2023

Modeling and therapeutic targeting of inflammation-induced hepatic insulin resistance using human iPSC-derived hepatocytes and macrophages.

Modeling and therapeutic targeting of inflammation-induced hepatic insulin resistance using human iPSC-derived hepatocytes and macrophages.

Journal: Nature communications

Published: October 07, 2022

The Role of STING in Liver Injury Is Both Stimulus- and Time-Dependent.

The Role of STING in Liver Injury Is Both Stimulus- and Time-Dependent.

Journal: Nutrients

Published: September 04, 2022

Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity.

Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity.

Journal: Cell biology and toxicology

Published: March 20, 2020

Induced Pluripotent Stem Cell-derived Hepatocytes From Patients With Nonalcoholic Fatty Liver Disease Display a Disease-specific Gene Expression Profile.

Induced Pluripotent Stem Cell-derived Hepatocytes From Patients With Nonalcoholic Fatty Liver Disease Display a Disease-specific Gene Expression Profile.

Journal: Gastroenterology

Published: October 27, 2019

Drug-induced liver injury in obesity and nonalcoholic fatty liver disease.

Drug-induced liver injury in obesity and nonalcoholic fatty liver disease.

Journal: Advances in pharmacology (San Diego, Calif.)

Published: July 17, 2019

Endotoxin regulates matrix genes increasing reactive oxygen species generation by intercellular communication between palmitate-treated hepatocyte and stellate cell.

Endotoxin regulates matrix genes increasing reactive oxygen species generation by intercellular communication between palmitate-treated hepatocyte and stellate cell.

Journal: Journal of cellular physiology

Published: May 16, 2018

Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure.

Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure.

Journal: Oxidative medicine and cellular longevity

Published: April 06, 2018

Showing 1-12 of 17

Last Updated: 09/26/2026