Duncan C. Humphries

Nine Edinburgh Bioquarter, 9 Little France Rd
Edinburgh, SCT EH164UX, United Kingdom

Last Updated: 09/26/2026

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Found 20 publications

Galectin-1 Induces the Production of Immune-Suppressive Cytokines in Human and Mouse T Cells.

Galectin-1 Induces the Production of Immune-Suppressive Cytokines in Human and Mouse T Cells.

Journal: International journal of molecular sciences

Published: September 21, 2024

Pharmacological Characterization of GB1908, a Selective Galectin-1 Carbohydrate Binding Domain Inhibitor for the Treatment of Cancer.

Pharmacological Characterization of GB1908, a Selective Galectin-1 Carbohydrate Binding Domain Inhibitor for the Treatment of Cancer.

Journal: Pharmacology

Published: July 24, 2024

Effect of GB1107, a novel galectin-3 inhibitor on pro-fibrotic signalling in the liver.

Effect of GB1107, a novel galectin-3 inhibitor on pro-fibrotic signalling in the liver.

Journal: European journal of pharmacology

Published: April 24, 2024

Specific in situ immuno-imaging of pulmonary-resident memory lymphocytes in human lungs.

Specific in situ immuno-imaging of pulmonary-resident memory lymphocytes in human lungs.

Journal: Frontiers in immunology

Published: November 16, 2022

An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE).

An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE).

Journal: American journal of respiratory and critical care medicine

Published: August 16, 2022

Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation.

Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation.

Journal: Frontiers in pharmacology

Published: May 20, 2022

The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair.

The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair.

Journal: Science immunology

Published: November 19, 2021

Pulmonary-Resident Memory Lymphocytes: Pivotal Orchestrators of Local Immunity Against Respiratory Infections.

Pulmonary-Resident Memory Lymphocytes: Pivotal Orchestrators of Local Immunity Against Respiratory Infections.

Journal: Frontiers in immunology

Published: July 09, 2021

Selective Myeloid Depletion of Galectin-3 Offers Protection Against Acute and Chronic Lung Injury.

Selective Myeloid Depletion of Galectin-3 Offers Protection Against Acute and Chronic Lung Injury.

Journal: Frontiers in pharmacology

Published: May 27, 2021

Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis.

Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis.

Journal: The European respiratory journal

Published: June 29, 2020

Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease.

Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease.

Journal: Journal of the American Society of Nephrology : JASN

Published: June 09, 2020

Activated neutrophil fluorescent imaging technique for human lungs.

Activated neutrophil fluorescent imaging technique for human lungs.

Journal: Scientific reports

Published: May 05, 2020

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Last Updated: 09/26/2026