Duncan C. Miller

Newcastle Upon Tyne, ENG NE17RU, United Kingdom

Last Updated: 09/26/2026

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Found 18 publications

GFRA2 Identifies Cardiac Progenitors and Mediates Cardiomyocyte Differentiation in a RET-Independent Signaling Pathway.

GFRA2 Identifies Cardiac Progenitors and Mediates Cardiomyocyte Differentiation in a RET-Independent Signaling Pathway.

Journal: Cell reports

Published: October 26, 2023

Modulation of ERK5 Activity as a Therapeutic Anti-Cancer Strategy.

Modulation of ERK5 Activity as a Therapeutic Anti-Cancer Strategy.

Journal: Journal of medicinal chemistry

Published: April 01, 2023

Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions.

Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions.

Journal: Journal of medicinal chemistry

Published: November 11, 2022

Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor.

Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor.

Journal: Journal of medicinal chemistry

Published: April 25, 2022

An Alkynylpyrimidine-Based Covalent Inhibitor That Targets a Unique Cysteine in NF-κB-Inducing Kinase.

An Alkynylpyrimidine-Based Covalent Inhibitor That Targets a Unique Cysteine in NF-κB-Inducing Kinase.

Journal: Journal of medicinal chemistry

Published: July 02, 2021

Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction.

Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction.

Journal: Journal of medicinal chemistry

Published: March 24, 2021

FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation.

FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation.

Journal: Journal of medicinal chemistry

Published: March 13, 2019

Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4.

Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4.

Journal: European journal of medicinal chemistry

Published: February 25, 2019

The discovery and optimization of benzimidazoles as selective NaV1.8 blockers for the treatment of pain.

The discovery and optimization of benzimidazoles as selective NaV1.8 blockers for the treatment of pain.

Journal: Bioorganic & medicinal chemistry

Published: August 22, 2018

Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach.

Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach.

Journal: Organic & biomolecular chemistry

Published: February 23, 2018

Ajmaline blocks INa and IKr without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters.

Ajmaline blocks INa and IKr without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters.

Journal: Stem cell research

Published: June 12, 2017

Generation of kisspeptin-responsive GnRH neurons from human pluripotent stem cells.

Generation of kisspeptin-responsive GnRH neurons from human pluripotent stem cells.

Journal: Molecular and cellular endocrinology

Published: November 03, 2016

Showing 1-12 of 18

Last Updated: 09/26/2026