Duncan Mchale

7 Denne Hill Business Centre, Womenswold, Kent
Canterbury, ENG CT46HD, United Kingdom

Last Updated: 09/26/2026

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Found 16 publications

Corrigendum to 'Intradiscal linezolid (PP353) treatment for chronic low back pain associated with Modic change type 1: an international, first-in-human, randomised, sham procedure-controlled, double-blind, phase 1b clinical trial' eClinicalMedicine 2026; 92: 103764.

Corrigendum to 'Intradiscal linezolid (PP353) treatment for chronic low back pain associated with Modic change type 1: an international, first-in-human, randomised, sham procedure-controlled, double-blind, phase 1b clinical trial' eClinicalMedicine 2026; 92: 103764.

Journal: EClinicalMedicine

Published: March 20, 2026

Intradiscal linezolid (PP353) treatment for chronic low back pain associated with Modic change type 1: an international, first-in-human, randomised, sham procedure-controlled, double-blind, phase 1b clinical trial.

Intradiscal linezolid (PP353) treatment for chronic low back pain associated with Modic change type 1: an international, first-in-human, randomised, sham procedure-controlled, double-blind, phase 1b clinical trial.

Journal: EClinicalMedicine

Published: August 29, 2025

Phase 1/2, open-label study of oral bacterial supplementation (EDP1503) plus pembrolizumab in participants with advanced or metastatic microsatellite-stable colorectal cancer, triple-negative breast cancer, and checkpoint inhibitor-relapsed tumors.

Phase 1/2, open-label study of oral bacterial supplementation (EDP1503) plus pembrolizumab in participants with advanced or metastatic microsatellite-stable colorectal cancer, triple-negative breast cancer, and checkpoint inhibitor-relapsed tumors.

Journal: Investigational new drugs

Published: May 19, 2025

Health Insurance Coverage Predicts Health Care Use among Latine Immigrants in Two Policy Contexts.

Health Insurance Coverage Predicts Health Care Use among Latine Immigrants in Two Policy Contexts.

Journal: Journal of health care for the poor and underserved

Published: June 03, 2024

Pharmacokinetics of PP353, a formulation of linezolid for intervertebral disc administration, in patients with chronic low back pain and Modic change Type 1: A first-in-human, Phase 1b, open-label, single-dose study.

Pharmacokinetics of PP353, a formulation of linezolid for intervertebral disc administration, in patients with chronic low back pain and Modic change Type 1: A first-in-human, Phase 1b, open-label, single-dose study.

Journal: JOR spine

Published: April 10, 2024

Modic changes as seen on MRI are associated with nonspecific chronic lower back pain and disability.

Modic changes as seen on MRI are associated with nonspecific chronic lower back pain and disability.

Journal: Journal of orthopaedic surgery and research

Published: March 03, 2023

A genome-wide screen for variants influencing certolizumab pegol response in a moderate to severe rheumatoid arthritis population.

A genome-wide screen for variants influencing certolizumab pegol response in a moderate to severe rheumatoid arthritis population.

Journal: PloS one

Published: December 11, 2020

Clinical spectrum of STX1B-related epileptic disorders.

Clinical spectrum of STX1B-related epileptic disorders.

Journal: Neurology

Published: April 05, 2018

Trial watch: Tracing investment in drug development for Alzheimer disease.

Trial watch: Tracing investment in drug development for Alzheimer disease.

Journal: Nature reviews. Drug discovery

Published: October 24, 2017

Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression.

Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression.

Journal: eLife

Published: December 01, 2016

Dominant Splice Site Mutations in PIK3R1 Cause Hyper IgM Syndrome, Lymphadenopathy and Short Stature.

Dominant Splice Site Mutations in PIK3R1 Cause Hyper IgM Syndrome, Lymphadenopathy and Short Stature.

Journal: Journal of clinical immunology

Published: February 12, 2016

The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.

The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.

Journal: Cell

Published: October 26, 2015

Showing 1-12 of 16

Last Updated: 09/26/2026