Last Updated: 09/26/2026
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Found 6 publications
Discovery of Nirmatrelvir (PF-07321332): A Potent, Orally Active Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) Main Protease.
Journal: Journal of medicinal chemistry
Published: February 28, 2025
Discovery of Clinical Candidate PF-06648671: A Potent γ-Secretase Modulator for the Treatment of Alzheimer's Disease.
Journal: Journal of medicinal chemistry
Published: June 07, 2024
Discovery of Potent and Selective Periphery-Restricted Quinazoline Inhibitors of the Cyclic Nucleotide Phosphodiesterase PDE1.
Journal: Journal of medicinal chemistry
Published: May 03, 2018
Design of Pyridopyrazine-1,6-dione γ-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability.
Journal: ACS medicinal chemistry letters
Published: February 11, 2015
Synthesis of α,α-difluoroethyl aryl and heteroaryl ethers.
Journal: Organic letters
Published: July 24, 2012
Showing 1-6 of 6
Last Updated: 09/26/2026