Eddy J. Van Roon

Rotterdam, ZH, Netherlands

Last Updated: 09/26/2026

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Found 8 publications

Antileukemic Efficacy of BET Inhibitor in a Preclinical Mouse Model of MLL-AF4+ Infant ALL.

Antileukemic Efficacy of BET Inhibitor in a Preclinical Mouse Model of MLL-AF4+ Infant ALL.

Journal: Molecular cancer therapeutics
Published: November 13, 2017

The HDAC inhibitor panobinostat (LBH589) exerts in vivo anti-leukaemic activity against MLL-rearranged acute lymphoblastic leukaemia and involves the RNF20/RNF40/WAC-H2B ubiquitination axis.

The HDAC inhibitor panobinostat (LBH589) exerts in vivo anti-leukaemic activity against MLL-rearranged acute lymphoblastic leukaemia and involves the RNF20/RNF40/WAC-H2B ubiquitination axis.

Journal: Leukemia
Published: November 10, 2016

Immunophenotypic analysis and quantification of B-1 and B-2 B cells during human fetal hematopoietic development.

Immunophenotypic analysis and quantification of B-1 and B-2 B cells during human fetal hematopoietic development.

Journal: Leukemia
Published: December 30, 2015

Cellular Ontogeny and Hierarchy Influence the Reprogramming Efficiency of Human B Cells into Induced Pluripotent Stem Cells.

Cellular Ontogeny and Hierarchy Influence the Reprogramming Efficiency of Human B Cells into Induced Pluripotent Stem Cells.

Journal: Stem cells (Dayton, Ohio)
Published: November 16, 2015

Identification of genes transcriptionally responsive to the loss of MLL fusions in MLL-rearranged acute lymphoblastic leukemia.

Identification of genes transcriptionally responsive to the loss of MLL fusions in MLL-rearranged acute lymphoblastic leukemia.

Journal: PloS one
Published: August 17, 2014

MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL.

MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL.

Journal: Cell cycle (Georgetown, Tex.)
Published: April 17, 2014

Frequencies and prognostic impact of RAS mutations in MLL-rearranged acute lymphoblastic leukemia in infants.

Frequencies and prognostic impact of RAS mutations in MLL-rearranged acute lymphoblastic leukemia in infants.

Journal: Haematologica
Published: February 14, 2013

Absence of global hypomethylation in promoter hypermethylated Mixed Lineage Leukaemia-rearranged infant acute lymphoblastic leukaemia.

Absence of global hypomethylation in promoter hypermethylated Mixed Lineage Leukaemia-rearranged infant acute lymphoblastic leukaemia.

Journal: European journal of cancer (Oxford, England : 1990)
Published: June 01, 2012
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Last Updated: 09/26/2026