Edgars Liepinsh

Dzirciema Str 16
Riga, RIX 1007, Latvia

Last Updated: 09/26/2026

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Found 81 publications

Complex Distribution Phenomena and Plastic Binding of Test Chemicals in Cell Culture Experiments: Exemplification by Tebufenpyrad.

Complex Distribution Phenomena and Plastic Binding of Test Chemicals in Cell Culture Experiments: Exemplification by Tebufenpyrad.

Journal: International journal of molecular sciences

Published: May 05, 2026

Gentamicin triggers fatty acid oxidation-dependent mitochondrial ROS, driving greater nephrotoxicity than apramycin and other aminoglycosides.

Gentamicin triggers fatty acid oxidation-dependent mitochondrial ROS, driving greater nephrotoxicity than apramycin and other aminoglycosides.

Journal: Free radical biology & medicine

Published: December 10, 2025

Testing Strategies for Metabolite-Mediated Neurotoxicity.

Testing Strategies for Metabolite-Mediated Neurotoxicity.

Journal: International journal of molecular sciences

Published: June 30, 2025

Low Bioavailability and High TMAO Production: Novel Insights Into Acetylcarnitine and Carnitine Metabolism.

Low Bioavailability and High TMAO Production: Novel Insights Into Acetylcarnitine and Carnitine Metabolism.

Journal: Molecular nutrition & food research

Published: April 07, 2025

LC-MS/MS-based simultaneous quantification of acylcarnitines, eicosapentaenoic acid, and docosahexaenoic acid: exploring potential biomarkers in human plasma.

LC-MS/MS-based simultaneous quantification of acylcarnitines, eicosapentaenoic acid, and docosahexaenoic acid: exploring potential biomarkers in human plasma.

Journal: Analytical and bioanalytical chemistry

Published: February 18, 2025

EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines.

EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines.

Journal: BioFactors (Oxford, England)

Published: November 26, 2024

Fatty acid β-oxidation in brain mitochondria: Insights from high-resolution respirometry in mouse, rat and Drosophila brain, ischemia and aging models.

Fatty acid β-oxidation in brain mitochondria: Insights from high-resolution respirometry in mouse, rat and Drosophila brain, ischemia and aging models.

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: July 31, 2024

PK/PD modelling and simulation of longitudinal meropenem in vivo effects against Escherichia coli and Klebsiella pneumoniae strains with high MICs.

PK/PD modelling and simulation of longitudinal meropenem in vivo effects against Escherichia coli and Klebsiella pneumoniae strains with high MICs.

Journal: International journal of antimicrobial agents

Published: July 04, 2024

Development of Potent Microtubule Targeting Agent by Structural Simplification of Natural Diazonamide.

Development of Potent Microtubule Targeting Agent by Structural Simplification of Natural Diazonamide.

Journal: Journal of medicinal chemistry

Published: June 04, 2024

Model-informed drug development for antimicrobials: translational pharmacokinetic-pharmacodynamic modelling of apramycin to facilitate prediction of efficacious dose in complicated urinary tract infections.

Model-informed drug development for antimicrobials: translational pharmacokinetic-pharmacodynamic modelling of apramycin to facilitate prediction of efficacious dose in complicated urinary tract infections.

Journal: The Journal of antimicrobial chemotherapy

Published: May 13, 2024

Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases.

Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases.

Journal: British journal of pharmacology

Published: April 23, 2024

Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria.

Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 05, 2024

Showing 1-12 of 81

Last Updated: 09/26/2026