Eduard Ayuso

Nantes, 44200, France

Last Updated: 09/26/2026

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Found 43 publications

Advancing liver gene therapy: Enhanced transduction with GalNAc-bioconjugated rAAV capsids.

Advancing liver gene therapy: Enhanced transduction with GalNAc-bioconjugated rAAV capsids.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: August 19, 2024

Ligand-modified rAAV6 vectors with nanoblades allow high-level gene knockin in HSPCs without compromising cell survival.

Ligand-modified rAAV6 vectors with nanoblades allow high-level gene knockin in HSPCs without compromising cell survival.

Journal: Molecular therapy. Nucleic acids
Published: May 29, 2024

Characterization of residual microRNAs in AAV vector batches produced in HEK293 mammalian cells and Sf9 insect cells.

Characterization of residual microRNAs in AAV vector batches produced in HEK293 mammalian cells and Sf9 insect cells.

Journal: Molecular therapy. Methods & clinical development
Published: February 27, 2024

Novel chemical tyrosine functionalization of adeno-associated virus improves gene transfer efficiency in liver and retina.

Novel chemical tyrosine functionalization of adeno-associated virus improves gene transfer efficiency in liver and retina.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: November 07, 2023

Mannose-coupled AAV2: A second-generation AAV vector for increased retinal gene therapy efficiency.

Mannose-coupled AAV2: A second-generation AAV vector for increased retinal gene therapy efficiency.

Journal: Molecular therapy. Methods & clinical development
Published: December 14, 2022

Human and Insect Cell-Produced Recombinant Adeno-Associated Viruses Show Differences in Genome Heterogeneity.

Human and Insect Cell-Produced Recombinant Adeno-Associated Viruses Show Differences in Genome Heterogeneity.

Journal: Human gene therapy
Published: March 16, 2022

Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells.

Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells.

Journal: Cell stem cell
Published: March 04, 2022

Liver-directed lentiviral gene therapy corrects hemophilia A mice and achieves normal-range factor VIII activity in non-human primates.

Liver-directed lentiviral gene therapy corrects hemophilia A mice and achieves normal-range factor VIII activity in non-human primates.

Journal: Nature communications
Published: August 30, 2021

Baboon Envelope Pseudotyped "Nanoblades" Carrying Cas9/gRNA Complexes Allow Efficient Genome Editing in Human T, B, and CD34+ Cells and Knock-in of AAV6-Encoded Donor DNA in CD34+ Cells.

Baboon Envelope Pseudotyped "Nanoblades" Carrying Cas9/gRNA Complexes Allow Efficient Genome Editing in Human T, B, and CD34+ Cells and Knock-in of AAV6-Encoded Donor DNA in CD34+ Cells.

Journal: Frontiers in genome editing
Published: September 09, 2020

Homologous Recombination Offers Advantages over Transposition-Based Systems to Generate Recombinant Baculovirus for Adeno-Associated Viral Vector Production.

Homologous Recombination Offers Advantages over Transposition-Based Systems to Generate Recombinant Baculovirus for Adeno-Associated Viral Vector Production.

Journal: Biotechnology journal
Published: May 14, 2020

The SSV-Seq 2.0 PCR-Free Method Improves the Sequencing of Adeno-Associated Viral Vector Genomes Containing GC-Rich Regions and Homopolymers.

The SSV-Seq 2.0 PCR-Free Method Improves the Sequencing of Adeno-Associated Viral Vector Genomes Containing GC-Rich Regions and Homopolymers.

Journal: Biotechnology journal
Published: May 14, 2020

Chemical modification of the adeno-associated virus capsid to improve gene delivery.

Chemical modification of the adeno-associated virus capsid to improve gene delivery.

Journal: Chemical science
Published: December 09, 2019
Showing 1-12 of 43

Last Updated: 09/26/2026