Edward P. Fielder

Newcastle Upon Tyne, ENG NE45PL, United Kingdom

Last Updated: 09/26/2026

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Found 16 publications

Activation of pro-survival autophagy by a small molecule promoting p62 oligomerisation.

Activation of pro-survival autophagy by a small molecule promoting p62 oligomerisation.

Journal: The Journal of biological chemistry
Published: July 23, 2025

In vivo modeling recapitulates radiotherapy delivery and late-effect profile for childhood medulloblastoma.

In vivo modeling recapitulates radiotherapy delivery and late-effect profile for childhood medulloblastoma.

Journal: Neuro-oncology advances
Published: July 01, 2024

Mild Uncoupling of Mitochondria Synergistically Enhances Senolytic Specificity and Sensitivity of BH3 Mimetics.

Mild Uncoupling of Mitochondria Synergistically Enhances Senolytic Specificity and Sensitivity of BH3 Mimetics.

Journal: Aging biology
Published: February 20, 2024

Senescent Dermal Fibroblasts Decrease Stemness in Basal Keratinocytes in a Bioengineered Model of Human Full-Thickness Skin.

Senescent Dermal Fibroblasts Decrease Stemness in Basal Keratinocytes in a Bioengineered Model of Human Full-Thickness Skin.

Journal: The Journal of investigative dermatology
Published: November 05, 2023

Short senolytic or senostatic interventions rescue progression of radiation-induced frailty and premature ageing in mice.

Short senolytic or senostatic interventions rescue progression of radiation-induced frailty and premature ageing in mice.

Journal: eLife
Published: November 11, 2021

Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice.

Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice.

Journal: Aging cell
Published: October 30, 2020

Anti-inflammatory treatment rescues memory deficits during aging in nfkb1-/- mice.

Anti-inflammatory treatment rescues memory deficits during aging in nfkb1-/- mice.

Journal: Aging cell
Published: April 13, 2020

Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis.

Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis.

Journal: Cell metabolism
Published: May 09, 2019

Mitochondrial dysfunction and cell senescence: deciphering a complex relationship.

Mitochondrial dysfunction and cell senescence: deciphering a complex relationship.

Journal: FEBS letters
Published: May 06, 2019

Sublethal whole-body irradiation causes progressive premature frailty in mice.

Sublethal whole-body irradiation causes progressive premature frailty in mice.

Journal: Mechanisms of ageing and development
Published: January 28, 2019

Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk.

Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk.

Journal: Nature communications
Published: January 17, 2019

Senolytics and senostatics as adjuvant tumour therapy.

Senolytics and senostatics as adjuvant tumour therapy.

Journal: EBioMedicine
Published: December 06, 2018
Showing 1-12 of 16

Last Updated: 09/26/2026