Edwin Rosa-Vazquez

San Juan PR 00931
San Juan, Puerto Rico

Last Updated: 09/26/2026

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Found 29 publications

Endothelial KLF4 depletion drives age-related neurovascular dysfunction and neuropsychiatric impairment.

Endothelial KLF4 depletion drives age-related neurovascular dysfunction and neuropsychiatric impairment.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: June 18, 2026

Inhibiting 15-PGDH restores redox homeostasis and confers neuroprotection in Parkinson's disease.

Inhibiting 15-PGDH restores redox homeostasis and confers neuroprotection in Parkinson's disease.

Journal: Redox biology

Published: May 13, 2026

P7C3-A20 prevents whole brain radiotherapy-induced chronic hippocampal redox imbalance and neuropsychiatric impairment in mice.

P7C3-A20 prevents whole brain radiotherapy-induced chronic hippocampal redox imbalance and neuropsychiatric impairment in mice.

Journal: Redox biology

Published: January 13, 2026

Cystathionine γ-lyase is a major regulator of cognitive function through neurotrophin signaling and neurogenesis.

Cystathionine γ-lyase is a major regulator of cognitive function through neurotrophin signaling and neurogenesis.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: December 26, 2025

Pharmacologic reversal of advanced Alzheimer's disease in mice and identification of potential therapeutic nodes in human brain.

Pharmacologic reversal of advanced Alzheimer's disease in mice and identification of potential therapeutic nodes in human brain.

Journal: Cell reports. Medicine

Published: June 23, 2025

Guanosine-Based Supramolecular Particles for Enhanced Drug and Gene Delivery in Cell Culture.

Guanosine-Based Supramolecular Particles for Enhanced Drug and Gene Delivery in Cell Culture.

Journal: ACS applied bio materials

Published: June 10, 2025

Inhibiting 15-PGDH blocks blood-brain barrier deterioration and protects mice from Alzheimer's disease and traumatic brain injury.

Inhibiting 15-PGDH blocks blood-brain barrier deterioration and protects mice from Alzheimer's disease and traumatic brain injury.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: May 21, 2025

Protein thiol alterations drive pathologic liquid-liquid phase separation in the aging brain.

Protein thiol alterations drive pathologic liquid-liquid phase separation in the aging brain.

Journal: Nature structural & molecular biology

Published: May 14, 2025

Cystic Fibrosis-related neurodegenerative disease associated with tauopathy and cognitive decline in aged CF mice.

Cystic Fibrosis-related neurodegenerative disease associated with tauopathy and cognitive decline in aged CF mice.

Journal: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

Published: February 11, 2025

Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury.

Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury.

Journal: Molecular neurodegeneration

Published: February 23, 2024

Acutely blocking excessive mitochondrial fission prevents chronic neurodegeneration after traumatic brain injury.

Acutely blocking excessive mitochondrial fission prevents chronic neurodegeneration after traumatic brain injury.

Journal: Cell reports. Medicine

Published: January 20, 2024

Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease.

Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: July 18, 2023

Showing 1-12 of 29

Last Updated: 09/26/2026