Efstratios Stratikos

Zografos, ESYE31 15784, Greece

Last Updated: 09/26/2026

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Found 85 publications

Discovery of an Orally Available Potent ER Aminopeptidase 1 (ERAP1) Inhibitor That Enhances Antitumor Responses and Limits Inflammatory Autoimmunity In Vivo.

Discovery of an Orally Available Potent ER Aminopeptidase 1 (ERAP1) Inhibitor That Enhances Antitumor Responses and Limits Inflammatory Autoimmunity In Vivo.

Journal: Journal of medicinal chemistry

Published: June 22, 2026

Automated Molecular Design in BRADSHAW, Applied to the Optimization of ERAP1 Inhibitors.

Automated Molecular Design in BRADSHAW, Applied to the Optimization of ERAP1 Inhibitors.

Journal: Journal of medicinal chemistry

Published: April 13, 2026

Method for Measuring the Kinetic Stability of Peptides Bound onto MHC Class I Using MALDI-TOF Mass Spectrometry.

Method for Measuring the Kinetic Stability of Peptides Bound onto MHC Class I Using MALDI-TOF Mass Spectrometry.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: January 01, 2026

The impact of ERAP1 inhibition on metabolite homeostasis of melanoma cells.

The impact of ERAP1 inhibition on metabolite homeostasis of melanoma cells.

Journal: Scientific reports

Published: October 29, 2025

ERAP1 Allotypes 2 and 10 Differentially Regulate the Immunopeptidome of Melanocytes.

ERAP1 Allotypes 2 and 10 Differentially Regulate the Immunopeptidome of Melanocytes.

Journal: Immunology

Published: July 31, 2025

Dantrolene is an HDL-associated paraoxonase-1 activator with immunosuppressive and atheroprotective properties.

Dantrolene is an HDL-associated paraoxonase-1 activator with immunosuppressive and atheroprotective properties.

Journal: Biochimica et biophysica acta. Molecular and cell biology of lipids

Published: October 16, 2024

ERAP1 Activity Modulates the Immunopeptidome but Also Affects the Proteome, Metabolism, and Stress Responses in Cancer Cells.

ERAP1 Activity Modulates the Immunopeptidome but Also Affects the Proteome, Metabolism, and Stress Responses in Cancer Cells.

Journal: Molecular & cellular proteomics : MCP

Published: September 22, 2024

Optimization of Potent and Selective Cyclohexyl Acid ERAP1 Inhibitors Using Structure- and Property-Based Drug Design.

Optimization of Potent and Selective Cyclohexyl Acid ERAP1 Inhibitors Using Structure- and Property-Based Drug Design.

Journal: ACS medicinal chemistry letters

Published: August 08, 2024

Stabilization of the open conformation οf insulin-regulated aminopeptidase by a novel substrate-selective small-molecule inhibitor.

Stabilization of the open conformation οf insulin-regulated aminopeptidase by a novel substrate-selective small-molecule inhibitor.

Journal: Protein science : a publication of the Protein Society

Published: June 06, 2024

Polymorphic positions 349 and 725 of the autoimmunity-protective allotype 10 of ER aminopeptidase 1 are key in determining its unique enzymatic properties.

Polymorphic positions 349 and 725 of the autoimmunity-protective allotype 10 of ER aminopeptidase 1 are key in determining its unique enzymatic properties.

Journal: Frontiers in immunology

Published: April 11, 2024

Library screening identifies commercial drugs as potential structure correctors of abnormal apolipoprotein A-I.

Library screening identifies commercial drugs as potential structure correctors of abnormal apolipoprotein A-I.

Journal: Journal of lipid research

Published: January 21, 2024

Mechanisms of Allosteric Inhibition of Insulin-Regulated Aminopeptidase.

Mechanisms of Allosteric Inhibition of Insulin-Regulated Aminopeptidase.

Journal: Journal of molecular biology

Published: December 02, 2023

Showing 1-12 of 85

Last Updated: 09/26/2026