Ela Hurley-Smiljanic

Mill Hill
London, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 8 publications

Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty.

Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty.

Journal: Bioorganic & medicinal chemistry letters

Published: July 01, 2019

Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines.

Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines.

Journal: Bioorganic & medicinal chemistry letters

Published: September 23, 2018

Discovery of potent and selective 5-azaindazole inhibitors of leucine-rich repeat kinase 2 (LRRK2) - Part 1.

Discovery of potent and selective 5-azaindazole inhibitors of leucine-rich repeat kinase 2 (LRRK2) - Part 1.

Journal: Bioorganic & medicinal chemistry letters

Published: August 16, 2018

Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG).

Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG).

Journal: Bioorganic & medicinal chemistry letters

Published: June 06, 2018

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.

Journal: Nature communications

Published: February 20, 2017

Biochemical and antiparasitic properties of inhibitors of the Plasmodium falciparum calcium-dependent protein kinase PfCDPK1.

Biochemical and antiparasitic properties of inhibitors of the Plasmodium falciparum calcium-dependent protein kinase PfCDPK1.

Journal: Antimicrobial agents and chemotherapy

Published: July 30, 2014

Imidazopyridazines as potent inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1): Preparation and evaluation of pyrazole linked analogues.

Imidazopyridazines as potent inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1): Preparation and evaluation of pyrazole linked analogues.

Journal: Bioorganic & medicinal chemistry letters

Published: June 18, 2013

Synthesis and structure-activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKε kinases.

Synthesis and structure-activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKε kinases.

Journal: Bioorganic & medicinal chemistry letters

Published: July 27, 2012

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Last Updated: 09/26/2026