Eleanor W. Trotter

Wilmslow Road
Wilmslow, ENG M204GJ, United Kingdom

Last Updated: 09/26/2026

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Found 16 publications

PKMYT1 has an important role in the timing and fidelity of chromosome segregation.

PKMYT1 has an important role in the timing and fidelity of chromosome segregation.

Journal: EMBO reports

Published: October 13, 2025

Systematic discovery of UFM1 receptors reveals a regulatory module in DNA repair directing non-homologous end-joining.

Systematic discovery of UFM1 receptors reveals a regulatory module in DNA repair directing non-homologous end-joining.

Journal: Nature communications

Published: September 22, 2025

Suppression of AKT Activation Through LZK Inhibition Limits Tumor Growth in Esophageal and Head and Neck Cancers.

Suppression of AKT Activation Through LZK Inhibition Limits Tumor Growth in Esophageal and Head and Neck Cancers.

Journal: Molecular cancer therapeutics

Published: September 04, 2025

Targeting c-MYC and gain-of-function p53 through inhibition or degradation of the kinase LZK suppresses the growth of HNSCC tumors.

Targeting c-MYC and gain-of-function p53 through inhibition or degradation of the kinase LZK suppresses the growth of HNSCC tumors.

Journal: Science signaling

Published: February 11, 2025

Targeting GOF p53 and c-MYC through LZK Inhibition or Degradation Suppresses Head and Neck Tumor Growth.

Targeting GOF p53 and c-MYC through LZK Inhibition or Degradation Suppresses Head and Neck Tumor Growth.

Journal: bioRxiv : the preprint server for biology

Published: November 28, 2024

Elevated basal AMP-activated protein kinase activity sensitizes colorectal cancer cells to growth inhibition by metformin.

Elevated basal AMP-activated protein kinase activity sensitizes colorectal cancer cells to growth inhibition by metformin.

Journal: Open biology

Published: April 12, 2023

Release from cell cycle arrest with Cdk4/6 inhibitors generates highly synchronized cell cycle progression in human cell culture.

Release from cell cycle arrest with Cdk4/6 inhibitors generates highly synchronized cell cycle progression in human cell culture.

Journal: Open biology

Published: October 14, 2020

Truncation- and motif-based pan-cancer analysis reveals tumor-suppressing kinases.

Truncation- and motif-based pan-cancer analysis reveals tumor-suppressing kinases.

Journal: Science signaling

Published: April 19, 2018

Survival of Head and Neck Cancer Cells Relies upon LZK Kinase-Mediated Stabilization of Mutant p53.

Survival of Head and Neck Cancer Cells Relies upon LZK Kinase-Mediated Stabilization of Mutant p53.

Journal: Cancer research

Published: February 01, 2017

Somatically mutated ABL1 is an actionable and essential NSCLC survival gene.

Somatically mutated ABL1 is an actionable and essential NSCLC survival gene.

Journal: EMBO molecular medicine

Published: January 14, 2016

Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis.

Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis.

Journal: Cancer research

Published: March 16, 2015

Discrepancies in cancer genomic sequencing highlight opportunities for driver mutation discovery.

Discrepancies in cancer genomic sequencing highlight opportunities for driver mutation discovery.

Journal: Cancer research

Published: September 27, 2014

Showing 1-12 of 16

Last Updated: 09/26/2026