Elena Aguilera

Ruta 3, C.P. 60000
Paysandu, PA 60000, Uruguay

Last Updated: 09/26/2026

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Found 15 publications

In vitro and in vivo studies of dehydroxylated-isoquines and -isotebuquines against trypanosomatids: a preclinical drug candidate for treatment of cutaneous leishmaniasis.

In vitro and in vivo studies of dehydroxylated-isoquines and -isotebuquines against trypanosomatids: a preclinical drug candidate for treatment of cutaneous leishmaniasis.

Journal: RSC medicinal chemistry

Published: January 05, 2026

A Novel Triose Phosphate Isomerase Inhibitor With Dual Trypanosomicidal Activity was Identified Using Artificial Intelligence-Based Virtual Screening.

A Novel Triose Phosphate Isomerase Inhibitor With Dual Trypanosomicidal Activity was Identified Using Artificial Intelligence-Based Virtual Screening.

Journal: ChemMedChem

Published: October 10, 2025

Unveiling novel pharmacophores and hit compounds for the development of anti-virals to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Unveiling novel pharmacophores and hit compounds for the development of anti-virals to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Journal: Bioorganic chemistry

Published: May 10, 2025

Looking for approved-medicines to be repositioned as anti-Trypanosoma cruzi agents. Identification of new chemotypes with good individual- or in combination-biological behaviours.

Looking for approved-medicines to be repositioned as anti-Trypanosoma cruzi agents. Identification of new chemotypes with good individual- or in combination-biological behaviours.

Journal: Memorias do Instituto Oswaldo Cruz

Published: August 15, 2024

Enzymatic Synthesis of Austroeupatol Esters with Enhanced Antiprotozoal Activity.

Enzymatic Synthesis of Austroeupatol Esters with Enhanced Antiprotozoal Activity.

Journal: ACS medicinal chemistry letters

Published: February 07, 2024

Optimization of the 2-arylquinazoline-4(3H)one scaffold for a selective and potent antitrypanosomal agent: modulation of the mechanism of action through chemical functionalization.

Optimization of the 2-arylquinazoline-4(3H)one scaffold for a selective and potent antitrypanosomal agent: modulation of the mechanism of action through chemical functionalization.

Journal: RSC medicinal chemistry

Published: May 26, 2023

Preclinical Studies and Drug Combination of Low-Cost Molecules for Chagas Disease.

Preclinical Studies and Drug Combination of Low-Cost Molecules for Chagas Disease.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: September 24, 2022

Preclinical Studies in Anti-Trypanosomatidae Drug Development.

Preclinical Studies in Anti-Trypanosomatidae Drug Development.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: June 02, 2021

Pyrazol(in)e derivatives of curcumin analogs as a new class of anti-Trypanosoma cruzi agents.

Pyrazol(in)e derivatives of curcumin analogs as a new class of anti-Trypanosoma cruzi agents.

Journal: Future medicinal chemistry

Published: March 02, 2021

Antiprotozoal Compounds from Urolepis hecatantha (Asteraceae).

Antiprotozoal Compounds from Urolepis hecatantha (Asteraceae).

Journal: Evidence-based complementary and alternative medicine : eCAM

Published: October 20, 2020

A Nature-Inspired Design Yields a New Class of Steroids Against Trypanosomatids.

A Nature-Inspired Design Yields a New Class of Steroids Against Trypanosomatids.

Journal: Molecules (Basel, Switzerland)

Published: August 17, 2019

Polypharmacology in the Treatment of Chagas Disease.

Polypharmacology in the Treatment of Chagas Disease.

Journal: Current medicinal chemistry

Published: January 02, 2018

Showing 1-12 of 15

Last Updated: 09/26/2026