Elena De Cecco

Zurich, ZH, Switzerland

Last Updated: 09/26/2026

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Found 25 publications

Prion propagation is controlled by a hierarchical network involving the nuclear Tfap2c and hnRNP K factors and the cytosolic mTORC1 complex.

Prion propagation is controlled by a hierarchical network involving the nuclear Tfap2c and hnRNP K factors and the cytosolic mTORC1 complex.

Journal: PLoS pathogens

Published: March 02, 2026

Large-scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation.

Large-scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation.

Journal: FEBS open bio

Published: February 19, 2026

Lysosomal escape and TMEM106B fibrillar core determine TDP-43 seeding outcomes.

Lysosomal escape and TMEM106B fibrillar core determine TDP-43 seeding outcomes.

Journal: bioRxiv : the preprint server for biology

Published: January 07, 2026

Large-scale seroepidemiology uncovers nephro-urological pathologies in people with tau autoimmunity.

Large-scale seroepidemiology uncovers nephro-urological pathologies in people with tau autoimmunity.

Journal: PLoS biology

Published: September 23, 2025

Prion-like transmission and propagation of human β-amyloid to the bank vole rodent model.

Prion-like transmission and propagation of human β-amyloid to the bank vole rodent model.

Journal: Acta neuropathologica

Published: September 16, 2025

Gpnmb defines a phagocytic state of microglia linked to cell death in prion disease mouse model.

Gpnmb defines a phagocytic state of microglia linked to cell death in prion disease mouse model.

Journal: Nature communications

Published: August 19, 2025

Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures.

Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures.

Journal: Neuron

Published: July 18, 2024

Arrayed CRISPR libraries for the genome-wide activation, deletion and silencing of human protein-coding genes.

Arrayed CRISPR libraries for the genome-wide activation, deletion and silencing of human protein-coding genes.

Journal: Nature biomedical engineering

Published: September 25, 2023

Different tau fibril types reduce prion level in chronically and de novo infected cells.

Different tau fibril types reduce prion level in chronically and de novo infected cells.

Journal: The Journal of biological chemistry

Published: January 16, 2023

The Hidden Cell-to-Cell Trail of α-Synuclein Aggregates.

The Hidden Cell-to-Cell Trail of α-Synuclein Aggregates.

Journal: Journal of molecular biology

Published: September 15, 2022

Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.

Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.

Journal: iScience

Published: August 16, 2022

Gerstmann-Sträussler-Scheinker Disease with F198S Mutation Induces Independent Tau and Prion Protein Pathologies in Bank Voles.

Gerstmann-Sträussler-Scheinker Disease with F198S Mutation Induces Independent Tau and Prion Protein Pathologies in Bank Voles.

Journal: Biomolecules

Published: August 10, 2022

Showing 1-12 of 25

Last Updated: 09/26/2026