Elian Dupre

Lille, 59000, France

Last Updated: 09/26/2026

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Found 25 publications

Tanycytic degeneration impairs tau clearance and contributes to Alzheimer's disease pathology.

Tanycytic degeneration impairs tau clearance and contributes to Alzheimer's disease pathology.

Journal: Cell press blue

Published: May 25, 2026

A Proline-Rich-Domain-Binding Single Domain Antibody Selectively Inhibits RNA-Induced Phase Separation of Tau.

A Proline-Rich-Domain-Binding Single Domain Antibody Selectively Inhibits RNA-Induced Phase Separation of Tau.

Journal: ACS chemical neuroscience

Published: May 08, 2026

A new chemotype that opens the S2∗ pocket of the 3CL protease exhibits antiviral activity against SARS-CoV-2.

A new chemotype that opens the S2∗ pocket of the 3CL protease exhibits antiviral activity against SARS-CoV-2.

Journal: European journal of medicinal chemistry

Published: October 01, 2025

Tau profiling of brain extracellular vesicles reveals PHF6 peptide as core for pathological tau seeding in Alzheimer's disease.

Tau profiling of brain extracellular vesicles reveals PHF6 peptide as core for pathological tau seeding in Alzheimer's disease.

Journal: Journal of biomedical science

Published: August 25, 2025

Anti-tau VHH therapy against PHF6: a safe approach to slowing the phenotype of tau pathology.

Anti-tau VHH therapy against PHF6: a safe approach to slowing the phenotype of tau pathology.

Journal: Alzheimer's research & therapy

Published: May 15, 2025

Aggregate-selective removal of pathological tau by clustering-activated degraders.

Aggregate-selective removal of pathological tau by clustering-activated degraders.

Journal: Science (New York, N.Y.)

Published: August 29, 2024

Inhibition of tau neuronal internalization using anti-tau single domain antibodies.

Inhibition of tau neuronal internalization using anti-tau single domain antibodies.

Journal: Nature communications

Published: July 16, 2024

Recombinant Production and Characterization of VHHs/Nanobodies Targeting Tau to Block Fibrillar Assembly.

Recombinant Production and Characterization of VHHs/Nanobodies Targeting Tau to Block Fibrillar Assembly.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: March 21, 2024

Magnetic resonance investigation of conformational responses of tau protein to specific phosphorylation.

Magnetic resonance investigation of conformational responses of tau protein to specific phosphorylation.

Journal: Biophysical chemistry

Published: July 23, 2023

A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein.

A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein.

Journal: The Journal of biological chemistry

Published: July 19, 2023

Conformation and Affinity Modulations by Multiple Phosphorylation Occurring in the BIN1 SH3 Domain Binding Site of the Tau Protein Proline-Rich Region.

Conformation and Affinity Modulations by Multiple Phosphorylation Occurring in the BIN1 SH3 Domain Binding Site of the Tau Protein Proline-Rich Region.

Journal: Biochemistry

Published: May 11, 2023

Novel dithiocarbamates selectively inhibit 3CL protease of SARS-CoV-2 and other coronaviruses.

Novel dithiocarbamates selectively inhibit 3CL protease of SARS-CoV-2 and other coronaviruses.

Journal: European journal of medicinal chemistry

Published: December 05, 2022

Showing 1-12 of 25

Last Updated: 09/26/2026