Elien Grajchen

Beerse, VLG, Belgium

Last Updated: 09/26/2026

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Found 14 publications

A sensitive LC‑MS/MS method for the simultaneous quantification of hexosylceramides and hexosylsphingosines, their precursors and metabolites in cells, plasma, and tissue homogenates.

A sensitive LC‑MS/MS method for the simultaneous quantification of hexosylceramides and hexosylsphingosines, their precursors and metabolites in cells, plasma, and tissue homogenates.

Journal: Analytical and bioanalytical chemistry

Published: January 21, 2026

Development and validation of a robust UPLC-MS/MS method for the analysis of polyamines in cells, biofluids and tissues.

Development and validation of a robust UPLC-MS/MS method for the analysis of polyamines in cells, biofluids and tissues.

Journal: Journal of pharmaceutical and biomedical analysis

Published: September 26, 2025

Fatty acid elongation by ELOVL6 hampers remyelination by promoting inflammatory foam cell formation during demyelination.

Fatty acid elongation by ELOVL6 hampers remyelination by promoting inflammatory foam cell formation during demyelination.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: September 05, 2023

Phloretin enhances remyelination by stimulating oligodendrocyte precursor cell differentiation.

Phloretin enhances remyelination by stimulating oligodendrocyte precursor cell differentiation.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: November 07, 2022

Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity.

Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity.

Journal: Cellular & molecular immunology

Published: September 09, 2022

The ApoA-I mimetic peptide 5A enhances remyelination by promoting clearance and degradation of myelin debris.

The ApoA-I mimetic peptide 5A enhances remyelination by promoting clearance and degradation of myelin debris.

Journal: Cell reports

Published: April 21, 2022

Phloretin suppresses neuroinflammation by autophagy-mediated Nrf2 activation in macrophages.

Phloretin suppresses neuroinflammation by autophagy-mediated Nrf2 activation in macrophages.

Journal: Journal of neuroinflammation

Published: March 16, 2021

Altered PPARγ Expression Promotes Myelin-Induced Foam Cell Formation in Macrophages in Multiple Sclerosis.

Altered PPARγ Expression Promotes Myelin-Induced Foam Cell Formation in Macrophages in Multiple Sclerosis.

Journal: International journal of molecular sciences

Published: November 26, 2020

CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation.

CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation.

Journal: Journal of neuroinflammation

Published: March 12, 2020

CNS delivery of anti-CD52 antibodies modestly reduces disease severity in an animal model for multiple sclerosis.

CNS delivery of anti-CD52 antibodies modestly reduces disease severity in an animal model for multiple sclerosis.

Journal: Therapeutic advances in chronic disease

Published: October 23, 2019

Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain.

Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain.

Journal: The Journal of experimental medicine

Published: September 05, 2019

The physiology of foamy phagocytes in multiple sclerosis.

The physiology of foamy phagocytes in multiple sclerosis.

Journal: Acta neuropathologica communications

Published: October 24, 2018

Showing 1-12 of 14

Last Updated: 09/26/2026