Elijah H. Lee

Seoul, Republic of Korea

Last Updated: 09/26/2026

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Found 12 publications

Design, Synthesis, and Biological Evaluation of Novel Vinyl Selenone Derivatives as Potent Nrf2 Activators for Atopic Dermatitis.

Design, Synthesis, and Biological Evaluation of Novel Vinyl Selenone Derivatives as Potent Nrf2 Activators for Atopic Dermatitis.

Journal: Journal of medicinal chemistry

Published: March 10, 2026

Synthetic Strategy and Evaluation of the Benzyloxy Benzylamide Derivatives as Thymic Stromal Lymphopoietin Modulators for the Treatment of Atopic Dermatitis.

Synthetic Strategy and Evaluation of the Benzyloxy Benzylamide Derivatives as Thymic Stromal Lymphopoietin Modulators for the Treatment of Atopic Dermatitis.

Journal: Journal of medicinal chemistry

Published: December 30, 2025

Oxidative stress-induced astrocytic collagen biosynthesis drives glial barrier formation and neuronal death in ischemic stroke.

Oxidative stress-induced astrocytic collagen biosynthesis drives glial barrier formation and neuronal death in ischemic stroke.

Journal: Cell metabolism

Published: September 17, 2025

Astrocytic monoamine oxidase B (MAOB)-gamma-aminobutyric acid (GABA) axis as a molecular brake on repair following spinal cord injury.

Astrocytic monoamine oxidase B (MAOB)-gamma-aminobutyric acid (GABA) axis as a molecular brake on repair following spinal cord injury.

Journal: Signal transduction and targeted therapy

Published: February 10, 2025

Hemoglobin as a pseudoperoxidase and drug target for oxidative stress-related diseases.

Hemoglobin as a pseudoperoxidase and drug target for oxidative stress-related diseases.

Journal: Signal transduction and targeted therapy

Published: January 21, 2025

Discovery and Optimization of a Series of Vinyl Sulfoximine-Based Analogues as Potent Nrf2 Activators for the Treatment of Multiple Sclerosis.

Discovery and Optimization of a Series of Vinyl Sulfoximine-Based Analogues as Potent Nrf2 Activators for the Treatment of Multiple Sclerosis.

Journal: Journal of medicinal chemistry

Published: September 26, 2024

Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease.

Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease.

Journal: Theranostics

Published: March 28, 2024

Optimization and evaluation of pyridinyl vinyl sulfones as Nrf2 activator for the antioxidant and anti-inflammatory effects.

Optimization and evaluation of pyridinyl vinyl sulfones as Nrf2 activator for the antioxidant and anti-inflammatory effects.

Journal: European journal of medicinal chemistry

Published: March 20, 2023

Synthesis and Evaluation of Serinolamide Derivatives as Sphingosine-1-Phosphate-1 (S1P1) Receptor Agonists.

Synthesis and Evaluation of Serinolamide Derivatives as Sphingosine-1-Phosphate-1 (S1P1) Receptor Agonists.

Journal: Molecules (Basel, Switzerland)

Published: April 04, 2022

Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis.

Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis.

Journal: Journal of medicinal chemistry

Published: January 25, 2022

Development and optimization of halogenated vinyl sulfones as Nrf2 activators for the treatment of Parkinson's disease.

Development and optimization of halogenated vinyl sulfones as Nrf2 activators for the treatment of Parkinson's disease.

Journal: European journal of medicinal chemistry

Published: September 07, 2020

Antioxidant, Anti-inflammatory, and Neuroprotective Effects of Novel Vinyl Sulfonate Compounds as Nrf2 Activator.

Antioxidant, Anti-inflammatory, and Neuroprotective Effects of Novel Vinyl Sulfonate Compounds as Nrf2 Activator.

Journal: ACS medicinal chemistry letters

Published: April 09, 2019

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Last Updated: 09/26/2026