Elisee Wiita

Stockholm, AB, Sweden

Last Updated: 09/26/2026

Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 30 publications

Structural basis for uracil removal from DNA by human SMUG1.

Structural basis for uracil removal from DNA by human SMUG1.

Journal: Nature communications
Published: October 27, 2025

Giving an Enzyme Scissors: Serotonin Derivatives as Potent Organocatalytic Switches for DNA Repair Enzyme OGG1.

Giving an Enzyme Scissors: Serotonin Derivatives as Potent Organocatalytic Switches for DNA Repair Enzyme OGG1.

Journal: Journal of medicinal chemistry
Published: October 15, 2025

Organocatalytic Switches of DNA Glycosylase OGG1 Catalyze a Highly Efficient AP-Lyase Function.

Organocatalytic Switches of DNA Glycosylase OGG1 Catalyze a Highly Efficient AP-Lyase Function.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)
Published: January 29, 2025

Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1.

Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1.

Journal: RSC chemical biology
Published: December 31, 2024

Virtual fragment screening for DNA repair inhibitors in vast chemical space.

Virtual fragment screening for DNA repair inhibitors in vast chemical space.

Journal: Nature communications
Published: April 27, 2024

The one-carbon metabolic enzyme MTHFD2 promotes resection and homologous recombination after ionizing radiation.

The one-carbon metabolic enzyme MTHFD2 promotes resection and homologous recombination after ionizing radiation.

Journal: Molecular oncology
Published: August 21, 2023

Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel.

Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel.

Journal: iScience
Published: November 12, 2022

Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells.

Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells.

Journal: Nature metabolism
Published: August 12, 2022

Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function.

Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function.

Journal: Science (New York, N.Y.)
Published: June 23, 2022

Optimization of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo-Guanine DNA Glycosylase 1.

Optimization of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo-Guanine DNA Glycosylase 1.

Journal: ChemMedChem
Published: June 03, 2022

The First Structure of Human MTHFD2L and Its Implications for the Development of Isoform-Selective Inhibitors.

The First Structure of Human MTHFD2L and Its Implications for the Development of Isoform-Selective Inhibitors.

Journal: ChemMedChem
Published: May 18, 2022

Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress.

Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress.

Journal: Nature cancer
Published: January 12, 2021
Showing 1-12 of 30

Last Updated: 09/26/2026