Elizabeth A. Cowley

Halifax, NS, Canada

Last Updated: 09/26/2026

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Found 13 publications

Functionally additive fixed positive and negative charges in the CFTR channel pore control anion binding and conductance.

Functionally additive fixed positive and negative charges in the CFTR channel pore control anion binding and conductance.

Journal: The Journal of biological chemistry

Published: October 26, 2021

Two positively charged amino acid side-chains in the inner vestibule of the CFTR channel pore play analogous roles in controlling anion binding and anion conductance.

Two positively charged amino acid side-chains in the inner vestibule of the CFTR channel pore play analogous roles in controlling anion binding and anion conductance.

Journal: Cellular and molecular life sciences : CMLS

Published: March 23, 2021

Electrostatic Tuning of Anion Attraction from the Cytoplasm to the Pore of the CFTR Chloride Channel.

Electrostatic Tuning of Anion Attraction from the Cytoplasm to the Pore of the CFTR Chloride Channel.

Journal: Cell biochemistry and biophysics

Published: November 22, 2019

Contribution of the eighth transmembrane segment to the function of the CFTR chloride channel pore.

Contribution of the eighth transmembrane segment to the function of the CFTR chloride channel pore.

Journal: Cellular and molecular life sciences : CMLS

Published: November 13, 2018

Functional organization of cytoplasmic portals controlling access to the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel pore.

Functional organization of cytoplasmic portals controlling access to the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel pore.

Journal: The Journal of biological chemistry

Published: December 08, 2017

Conformational change of the extracellular parts of the CFTR protein during channel gating.

Conformational change of the extracellular parts of the CFTR protein during channel gating.

Journal: Cellular and molecular life sciences : CMLS

Published: November 28, 2017

Contribution of a leucine residue in the first transmembrane segment to the selectivity filter region in the CFTR chloride channel.

Contribution of a leucine residue in the first transmembrane segment to the selectivity filter region in the CFTR chloride channel.

Journal: Biochimica et biophysica acta. Biomembranes

Published: November 18, 2016

Mast cells protect against Pseudomonas aeruginosa-induced lung injury.

Mast cells protect against Pseudomonas aeruginosa-induced lung injury.

Journal: The American journal of pathology

Published: January 17, 2014

Organic cation transporters in human nasal primary culture: expression and functional activity.

Organic cation transporters in human nasal primary culture: expression and functional activity.

Journal: Therapeutic delivery

Published: April 06, 2013

Development and characterization of a 3D multicell microtissue culture model of airway smooth muscle.

Development and characterization of a 3D multicell microtissue culture model of airway smooth muscle.

Journal: American journal of physiology. Lung cellular and molecular physiology

Published: November 06, 2012

Optimization of human nasal epithelium primary culture conditions for optimal proton oligopeptide and organic cation transporters expression in vitro.

Optimization of human nasal epithelium primary culture conditions for optimal proton oligopeptide and organic cation transporters expression in vitro.

Journal: International journal of pharmaceutics

Published: July 06, 2012

Pseudohalide anions reveal a novel extracellular site for potentiators to increase CFTR function.

Pseudohalide anions reveal a novel extracellular site for potentiators to increase CFTR function.

Journal: British journal of pharmacology

Published: May 23, 2012

Showing 1-12 of 13

Last Updated: 09/26/2026