Elizabeth C. Ledgerwood

Dunedin, OTA, New Zealand

Last Updated: 09/26/2026

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Found 22 publications

CALR Type 1-Like Mutations Increase Endoplasmic Reticulum Free Ca2+ and Induce ERK1/2 Activation Independent of Thrombopoietin Receptor Activation.

CALR Type 1-Like Mutations Increase Endoplasmic Reticulum Free Ca2+ and Induce ERK1/2 Activation Independent of Thrombopoietin Receptor Activation.

Journal: Cell biology international

Published: February 10, 2025

Biomarkers of Oxidative and Mitochondrial Stress Are Associated With Accelerated Pace of Aging at Midlife in a Birth Cohort.

Biomarkers of Oxidative and Mitochondrial Stress Are Associated With Accelerated Pace of Aging at Midlife in a Birth Cohort.

Journal: The journals of gerontology. Series A, Biological sciences and medical sciences

Published: January 26, 2025

Megakaryocyte maturation involves activation of the adaptive unfolded protein response.

Megakaryocyte maturation involves activation of the adaptive unfolded protein response.

Journal: Genes to cells : devoted to molecular & cellular mechanisms

Published: February 12, 2024

The Y49H cytochrome c variant enhances megakaryocytic maturation of K-562 cells.

The Y49H cytochrome c variant enhances megakaryocytic maturation of K-562 cells.

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: October 31, 2023

Inherited thrombocytopenia associated with a variant in the FLI1 binding site in the 5' UTR of ANKRD26.

Inherited thrombocytopenia associated with a variant in the FLI1 binding site in the 5' UTR of ANKRD26.

Journal: Clinical genetics

Published: October 24, 2023

A novel RNF125 variant associated with Tenorio syndrome alters ubiquitin chain binding.

A novel RNF125 variant associated with Tenorio syndrome alters ubiquitin chain binding.

Journal: Clinical genetics

Published: September 17, 2023

Altered conformational dynamics contribute to species-specific effects of cytochrome c mutations on caspase activation.

Altered conformational dynamics contribute to species-specific effects of cytochrome c mutations on caspase activation.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry

Published: July 27, 2023

Insights into H2O2-induced signaling in Jurkat cells from analysis of gene expression.

Insights into H2O2-induced signaling in Jurkat cells from analysis of gene expression.

Journal: Free radical research

Published: January 11, 2023

A novel frameshift GP1BB mutation causes autosomal dominant macrothrombocytopenia with decreased vWF receptor expression but normal platelet aggregation.

A novel frameshift GP1BB mutation causes autosomal dominant macrothrombocytopenia with decreased vWF receptor expression but normal platelet aggregation.

Journal: Platelets

Published: April 05, 2021

The Structure and Ubiquitin Binding Properties of TRAF RING Heterodimers.

The Structure and Ubiquitin Binding Properties of TRAF RING Heterodimers.

Journal: Journal of molecular biology

Published: December 18, 2020

Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity.

Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity.

Journal: The Biochemical journal

Published: October 11, 2020

CYCS gene variants associated with thrombocytopenia.

CYCS gene variants associated with thrombocytopenia.

Journal: Platelets

Published: November 20, 2018

Showing 1-12 of 22

Last Updated: 09/26/2026