Last Updated: 09/26/2026
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Found 13 publications
Discovery of EGT710, an Oral Nonpeptidomimetic Reversible Covalent SARS-CoV-2 Main Protease Inhibitor.
Journal: Journal of medicinal chemistry
Published: February 09, 2026
Discovery and Optimization of First-in-Class Molecular Glue Degraders of the WIZ Transcription Factor for Fetal Hemoglobin Induction to Treat Sickle Cell Disease.
Journal: Journal of medicinal chemistry
Published: November 14, 2024
Identification of Potent, Broad-Spectrum Coronavirus Main Protease Inhibitors for Pandemic Preparedness.
Journal: Journal of medicinal chemistry
Published: September 27, 2024
A molecular glue degrader of the WIZ transcription factor for fetal hemoglobin induction.
Journal: Science (New York, N.Y.)
Published: July 04, 2024
Crystal Structures of Inhibitor-Bound Main Protease from Delta- and Gamma-Coronaviruses.
Journal: Viruses
Published: January 31, 2023
Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy.
Journal: Cell chemical biology
Published: June 11, 2022
Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors.
Journal: Nature microbiology
Published: March 20, 2020
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.
Journal: Nature chemical biology
Published: October 15, 2018
Rationally Designed PI3Kα Mutants to Mimic ATR and Their Use to Understand Binding Specificity of ATR Inhibitors.
Journal: Journal of molecular biology
Published: February 03, 2017
Novel potent and selective inhibitors of p90 ribosomal S6 kinase reveal the heterogeneity of RSK function in MAPK-driven cancers.
Journal: Molecular cancer research : MCR
Published: February 21, 2014
Last Updated: 09/26/2026