Elwy H. Abdelkader

ARC Centre Of Excellence For Innovations In Peptide And Protein Science
Canberra, ACT, Australia

Last Updated: 09/26/2026

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Found 27 publications

Isosteric Engineering of Enzymes: Overcoming Activity-Stability Trade-Offs by Site-Selective CH → N Substitutions.

Isosteric Engineering of Enzymes: Overcoming Activity-Stability Trade-Offs by Site-Selective CH → N Substitutions.

Journal: Angewandte Chemie (International ed. in English)
Published: February 24, 2026

Characterising Side Chain Conformations in Proteins Using 19F-ENDOR and New Fluorinated Amino Acid Spin Labels.

Characterising Side Chain Conformations in Proteins Using 19F-ENDOR and New Fluorinated Amino Acid Spin Labels.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)
Published: September 01, 2025

Comparative evaluation of noncanonical amino acids as site-specific NMR probes for the complex of E. coli SSB with single-stranded DNA without isotope labelling.

Comparative evaluation of noncanonical amino acids as site-specific NMR probes for the complex of E. coli SSB with single-stranded DNA without isotope labelling.

Journal: The FEBS journal
Published: August 15, 2025

Genetic Encoding of Fluorinated Analogues of Phenylalanine for 19F NMR Spectroscopy: Detection of Conformational Heterogeneity in Flaviviral NS2B-NS3 Proteases.

Genetic Encoding of Fluorinated Analogues of Phenylalanine for 19F NMR Spectroscopy: Detection of Conformational Heterogeneity in Flaviviral NS2B-NS3 Proteases.

Journal: ACS sensors
Published: April 01, 2025

Rendering Proteins Fluorescent Inconspicuously: Genetically Encoded 4-Cyanotryptophan Conserves Their Structure and Enables the Detection of Ligand Binding Sites.

Rendering Proteins Fluorescent Inconspicuously: Genetically Encoded 4-Cyanotryptophan Conserves Their Structure and Enables the Detection of Ligand Binding Sites.

Journal: Angewandte Chemie (International ed. in English)
Published: October 29, 2024

A lanthanide tag for a complementary set of pseudocontact shifts.

A lanthanide tag for a complementary set of pseudocontact shifts.

Journal: Chemical communications (Cambridge, England)
Published: July 23, 2024

(2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5'-Difluoroleucine in Escherichia coli PpiB: Protein Production, 19F NMR, and Ligand Sensing Enhanced by the γ-Gauche Effect.

(2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5'-Difluoroleucine in Escherichia coli PpiB: Protein Production, 19F NMR, and Ligand Sensing Enhanced by the γ-Gauche Effect.

Journal: Biochemistry
Published: May 16, 2024

Conformational Preferences of the Non-Canonical Amino Acids (2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5'-Difluoroleucine in a Protein.

Conformational Preferences of the Non-Canonical Amino Acids (2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5'-Difluoroleucine in a Protein.

Journal: Biochemistry
Published: May 14, 2024

Ligand-induced conformational changes in protein molecules detected by sum-frequency generation.

Ligand-induced conformational changes in protein molecules detected by sum-frequency generation.

Journal: Biophysical journal
Published: March 11, 2024

Genetic Encoding of 7-Aza-l-tryptophan: Isoelectronic Substitution of a Single CH-Group in a Protein for a Nitrogen Atom for Site-Selective Isotope Labeling.

Genetic Encoding of 7-Aza-l-tryptophan: Isoelectronic Substitution of a Single CH-Group in a Protein for a Nitrogen Atom for Site-Selective Isotope Labeling.

Journal: ACS sensors
Published: October 27, 2023

Probing Ligand Binding Sites on Large Proteins by Nuclear Magnetic Resonance Spectroscopy of Genetically Encoded Non-Canonical Amino Acids.

Probing Ligand Binding Sites on Large Proteins by Nuclear Magnetic Resonance Spectroscopy of Genetically Encoded Non-Canonical Amino Acids.

Journal: Journal of medicinal chemistry
Published: March 15, 2023

Short-range ENDOR distance measurements between Gd(III) and trifluoromethyl labels in proteins.

Short-range ENDOR distance measurements between Gd(III) and trifluoromethyl labels in proteins.

Journal: Physical chemistry chemical physics : PCCP
Published: October 12, 2022
Showing 1-12 of 27

Last Updated: 09/26/2026