Emadeldin M. Kamel

Bani Suwayf, BNS, Egypt

Last Updated: 09/26/2026

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Found 106 publications

Breaking the Myb-KIX Alliance: Structure-Guided Discovery of Biaryl Hydroxy-Naphthamides as Disruptors of the c-Myb-CBP/p300 KIX Protein-Protein Interaction.

Breaking the Myb-KIX Alliance: Structure-Guided Discovery of Biaryl Hydroxy-Naphthamides as Disruptors of the c-Myb-CBP/p300 KIX Protein-Protein Interaction.

Journal: Archiv der Pharmazie

Published: June 18, 2026

Diaryl terephthalamides as small-molecule disruptors of the c-Myb-CBP/p300 KIX protein-protein interaction: Mechanistic insights and biochemical validation.

Diaryl terephthalamides as small-molecule disruptors of the c-Myb-CBP/p300 KIX protein-protein interaction: Mechanistic insights and biochemical validation.

Journal: Biochemical and biophysical research communications

Published: May 21, 2026

Structure-guided delineation of umbelliferyl phosphate-based disruptors of the c-Myb-CBP/p300 KIX protein-protein interaction.

Structure-guided delineation of umbelliferyl phosphate-based disruptors of the c-Myb-CBP/p300 KIX protein-protein interaction.

Journal: Biophysical chemistry

Published: May 07, 2026

Oxygenated 9H-carbazole-3-carbaldehyde scaffolds as cerebral cavernous malformation-relevant protein-protein interaction disruptors of the HEG1-KRIT1 interface.

Oxygenated 9H-carbazole-3-carbaldehyde scaffolds as cerebral cavernous malformation-relevant protein-protein interaction disruptors of the HEG1-KRIT1 interface.

Journal: Journal of computer-aided molecular design

Published: May 05, 2026

Targeting the c-Myb-CBP/p300 KIX protein-protein interaction with quinone-methide triterpenes: In silico mechanistic insights and MST biochemical validation.

Targeting the c-Myb-CBP/p300 KIX protein-protein interaction with quinone-methide triterpenes: In silico mechanistic insights and MST biochemical validation.

Journal: Journal of molecular graphics & modelling

Published: May 01, 2026

1H-Indazole-3-Carboxylic Acid Derivatives as Disruptors of the Oncogenic MTDH-SND1 Protein-Protein Interaction: An In Silico-to-In Vitro Study.

1H-Indazole-3-Carboxylic Acid Derivatives as Disruptors of the Oncogenic MTDH-SND1 Protein-Protein Interaction: An In Silico-to-In Vitro Study.

Journal: Cell biochemistry and biophysics

Published: April 17, 2026

Discovery of [1,2,4]triazolo[1,5-a]pyrimidine-based disruptors of the Skp2-Cks1 protein-protein interaction through integrated computational and experimental analysis.

Discovery of [1,2,4]triazolo[1,5-a]pyrimidine-based disruptors of the Skp2-Cks1 protein-protein interaction through integrated computational and experimental analysis.

Journal: Biochemical and biophysical research communications

Published: March 27, 2026

Structure-based discovery of diphenylpyrazines as disruptors of the Skp2-Cks1 protein-protein interaction: computational insights and biochemical validation.

Structure-based discovery of diphenylpyrazines as disruptors of the Skp2-Cks1 protein-protein interaction: computational insights and biochemical validation.

Journal: Journal of computer-aided molecular design

Published: March 25, 2026

Structure-Based Discovery of N-Aryl-N'-Heteroaryl Ureas as Disruptors of the Oncogenic MTDH-SND1 Protein-Protein Interaction: In Silico Insights and Biochemical Validation.

Structure-Based Discovery of N-Aryl-N'-Heteroaryl Ureas as Disruptors of the Oncogenic MTDH-SND1 Protein-Protein Interaction: In Silico Insights and Biochemical Validation.

Journal: Archiv der Pharmazie

Published: March 11, 2026

Structure-guided identification of 2-arylbenzothiazoles as disruptors of the oncogenic MTDH-SND1 protein-protein interaction.

Structure-guided identification of 2-arylbenzothiazoles as disruptors of the oncogenic MTDH-SND1 protein-protein interaction.

Journal: Archives of biochemistry and biophysics

Published: March 10, 2026

Disrupting the tumor-associated TNKS-USP25 protein-protein interface in cancer: structural basis, druggability, and therapeutic opportunities.

Disrupting the tumor-associated TNKS-USP25 protein-protein interface in cancer: structural basis, druggability, and therapeutic opportunities.

Journal: RSC advances

Published: February 15, 2026

Protein-protein interaction disruption as a next-generation antithrombotic strategy.

Protein-protein interaction disruption as a next-generation antithrombotic strategy.

Journal: Journal of thrombosis and thrombolysis

Published: February 11, 2026

Showing 1-12 of 106

Last Updated: 09/26/2026