Eman E. Dokla

Cairo, C 11566, Egypt

Last Updated: 09/26/2026

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Found 17 publications

FLT3 inhibitors in AML: from classic scaffolds to next-generation approaches.

FLT3 inhibitors in AML: from classic scaffolds to next-generation approaches.

Journal: RSC advances

Published: February 14, 2026

Activation of the Hippo Pathway by ATN Suppresses Cancer Stem-Like Properties and EGFR-Associated Signaling in Castration-Resistant Prostate Cancer Cells in vitro.

Activation of the Hippo Pathway by ATN Suppresses Cancer Stem-Like Properties and EGFR-Associated Signaling in Castration-Resistant Prostate Cancer Cells in vitro.

Journal: International journal of medical sciences

Published: December 13, 2025

Tackling microbial resistance with 4H-chromen-4-one derivatives as a novel class of penicillin binding protein 2a inhibitors.

Tackling microbial resistance with 4H-chromen-4-one derivatives as a novel class of penicillin binding protein 2a inhibitors.

Journal: Bioorganic & medicinal chemistry

Published: June 18, 2025

Structural Optimization and MD Simulation Study of Benzimidazole Derivatives as Potent Mutant FLT3 Kinase Inhibitors Targeting AML.

Structural Optimization and MD Simulation Study of Benzimidazole Derivatives as Potent Mutant FLT3 Kinase Inhibitors Targeting AML.

Journal: Archiv der Pharmazie

Published: January 20, 2025

A synthetic molecule targeting STAT3 against human oral squamous cell carcinoma cells.

A synthetic molecule targeting STAT3 against human oral squamous cell carcinoma cells.

Journal: International journal of medical sciences

Published: October 14, 2024

Anticancer activity of EMD37 against human head and neck cancer: Impact on apoptotic and inflammatory machineries.

Anticancer activity of EMD37 against human head and neck cancer: Impact on apoptotic and inflammatory machineries.

Journal: Toxicology in vitro : an international journal published in association with BIBRA

Published: June 24, 2024

FLT3-PROTACs for combating AML resistance: Analytical overview on chimeric agents developed, challenges, and future perspectives.

FLT3-PROTACs for combating AML resistance: Analytical overview on chimeric agents developed, challenges, and future perspectives.

Journal: European journal of medicinal chemistry

Published: May 16, 2024

Novel sulfonamide-indolinone hybrids targeting mitochondrial respiration of breast cancer cells.

Novel sulfonamide-indolinone hybrids targeting mitochondrial respiration of breast cancer cells.

Journal: European journal of medicinal chemistry

Published: January 14, 2024

FLT3 inhibitors and novel therapeutic strategies to reverse AML resistance: An updated comprehensive review.

FLT3 inhibitors and novel therapeutic strategies to reverse AML resistance: An updated comprehensive review.

Journal: Critical reviews in oncology/hematology

Published: April 01, 2023

SAR investigation and optimization of benzimidazole-based derivatives as antimicrobial agents against Gram-negative bacteria.

SAR investigation and optimization of benzimidazole-based derivatives as antimicrobial agents against Gram-negative bacteria.

Journal: European journal of medicinal chemistry

Published: September 09, 2022

Discovery of EMD37, a 1,2,4-oxadiazole derivative, as a novel endoplasmic reticulum stress inducer with potent anticancer activity.

Discovery of EMD37, a 1,2,4-oxadiazole derivative, as a novel endoplasmic reticulum stress inducer with potent anticancer activity.

Journal: Biochemical pharmacology

Published: August 18, 2022

Induction of apoptosis using ATN as a novel Yes-associated protein inhibitor in human oral squamous cell carcinoma cells.

Induction of apoptosis using ATN as a novel Yes-associated protein inhibitor in human oral squamous cell carcinoma cells.

Journal: Environmental toxicology

Published: September 22, 2021

Showing 1-12 of 17

Last Updated: 09/26/2026