Eman M. Zaghloul

Stockholm, AB 14186, Sweden

Last Updated: 09/26/2026

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Found 12 publications

Chemical Modifications and Design Influence the Potency of Huntingtin Anti-Gene Oligonucleotides.

Chemical Modifications and Design Influence the Potency of Huntingtin Anti-Gene Oligonucleotides.

Journal: Nucleic acid therapeutics
Published: February 03, 2023

Oligonucleotides Targeting DNA Repeats Downregulate Huntingtin Gene Expression in Huntington's Patient-Derived Neural Model System.

Oligonucleotides Targeting DNA Repeats Downregulate Huntingtin Gene Expression in Huntington's Patient-Derived Neural Model System.

Journal: Nucleic acid therapeutics
Published: September 14, 2021

Novel Orthogonally Hydrocarbon-Modified Cell-Penetrating Peptide Nanoparticles Mediate Efficient Delivery of Splice-Switching Antisense Oligonucleotides In Vitro and In Vivo.

Novel Orthogonally Hydrocarbon-Modified Cell-Penetrating Peptide Nanoparticles Mediate Efficient Delivery of Splice-Switching Antisense Oligonucleotides In Vitro and In Vivo.

Journal: Biomedicines
Published: July 20, 2021

Novel peptide-dendrimer/lipid/oligonucleotide ternary complexes for efficient cellular uptake and improved splice-switching activity.

Novel peptide-dendrimer/lipid/oligonucleotide ternary complexes for efficient cellular uptake and improved splice-switching activity.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
Published: May 09, 2018

Single-Stranded Nucleic Acids Regulate TLR3/4/7 Activation through Interference with Clathrin-Mediated Endocytosis.

Single-Stranded Nucleic Acids Regulate TLR3/4/7 Activation through Interference with Clathrin-Mediated Endocytosis.

Journal: Scientific reports
Published: April 25, 2018

Fast and efficient synthesis of Zorro-LNA type 3'-5'-5'-3' oligonucleotide conjugates via parallel in situ stepwise conjugation.

Fast and efficient synthesis of Zorro-LNA type 3'-5'-5'-3' oligonucleotide conjugates via parallel in situ stepwise conjugation.

Journal: Organic & biomolecular chemistry
Published: March 16, 2016

Delivery, Effect on Cell Viability, and Plasticity of Modified Aptamer Constructs.

Delivery, Effect on Cell Viability, and Plasticity of Modified Aptamer Constructs.

Journal: Nucleic acid therapeutics
Published: February 10, 2016

CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression.

CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression.

Journal: Nucleic acids research
Published: December 16, 2015

Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency.

Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency.

Journal: Molecular therapy. Nucleic acids
Published: September 29, 2015

Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes.

Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes.

Journal: Nucleic acids research
Published: June 29, 2015

Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA.

Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA.

Journal: Nucleic acids research
Published: January 25, 2013

Solid formulation of cell-penetrating peptide nanocomplexes with siRNA and their stability in simulated gastric conditions.

Solid formulation of cell-penetrating peptide nanocomplexes with siRNA and their stability in simulated gastric conditions.

Journal: Journal of controlled release : official journal of the Controlled Release Society
Published: February 04, 2012
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Last Updated: 09/26/2026