Emanuel J. Novais
Lisbon, Portugal
Last Updated: 09/26/2026
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Found 13 publications
Genetics- and age-driven neuroimmune and disc changes underscore herniation susceptibility and pain-associated behaviors in SM/J mice.
Journal: Science advances
Published: April 23, 2025
A new perspective on intervertebral disc calcification-from bench to bedside.
Journal: Bone research
Published: October 15, 2023
Failure of cartilage regeneration: emerging hypotheses and related therapeutic strategies.
Journal: Nature reviews. Rheumatology
Published: May 05, 2023
Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice.
Journal: Nature communications
Published: December 07, 2020
Hypoxia and Hypoxia-Inducible Factor-1α Regulate Endoplasmic Reticulum Stress in Nucleus Pulposus Cells: Implications of Endoplasmic Reticulum Stress for Extracellular Matrix Secretion.
Journal: The American journal of pathology
Published: September 06, 2020
Alterations in ECM signature underscore multiple sub-phenotypes of intervertebral disc degeneration.
Alterations in ECM signature underscore multiple sub-phenotypes of intervertebral disc degeneration.
Journal: Matrix biology plus
Published: February 14, 2020
TonEBP-deficiency accelerates intervertebral disc degeneration underscored by matrix remodeling, cytoskeletal rearrangements, and changes in proinflammatory gene expression.
Journal: Matrix biology : journal of the International Society for Matrix Biology
Published: August 01, 2019
Comparison of inbred mouse strains shows diverse phenotypic outcomes of intervertebral disc aging.
Journal: Aging cell
Published: July 26, 2019
Lactate Efflux From Intervertebral Disc Cells Is Required for Maintenance of Spine Health.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Published: July 03, 2019
Last Updated: 09/26/2026