Emiliano Pasquini

Lugano, TI, Switzerland

Last Updated: 09/26/2026

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Found 19 publications

Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability.

Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability.

Journal: Nature cell biology

Published: September 10, 2025

Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway.

Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway.

Journal: Immunity

Published: January 11, 2024

Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer.

Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer.

Journal: Cancer cell

Published: December 06, 2023

Author Correction: Single-cell transcriptomics identifies Mcl-1 as a target for senolytic therapy in cancer.

Author Correction: Single-cell transcriptomics identifies Mcl-1 as a target for senolytic therapy in cancer.

Journal: Nature communications

Published: July 20, 2023

Targeting senescence induced by age or chemotherapy with a polyphenol-rich natural extract improves longevity and healthspan in mice.

Targeting senescence induced by age or chemotherapy with a polyphenol-rich natural extract improves longevity and healthspan in mice.

Journal: Nature aging

Published: June 11, 2023

Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells.

Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells.

Journal: Cancer cell

Published: May 17, 2023

Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development.

Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development.

Journal: iScience

Published: April 05, 2023

VSSP-activated macrophages mediate senescence and tumor inhibition in a preclinical model of advanced prostate cancer.

VSSP-activated macrophages mediate senescence and tumor inhibition in a preclinical model of advanced prostate cancer.

Journal: Cell communication and signaling : CCS

Published: November 18, 2022

The Akt/mTOR and MNK/eIF4E pathways rewire the prostate cancer translatome to secrete HGF, SPP1 and BGN and recruit suppressive myeloid cells.

The Akt/mTOR and MNK/eIF4E pathways rewire the prostate cancer translatome to secrete HGF, SPP1 and BGN and recruit suppressive myeloid cells.

Journal: Nature cancer

Published: May 09, 2022

Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer.

Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer.

Journal: Cancer cell

Published: April 12, 2022

Commensal bacteria promote endocrine resistance in prostate cancer through androgen biosynthesis.

Commensal bacteria promote endocrine resistance in prostate cancer through androgen biosynthesis.

Journal: Science (New York, N.Y.)

Published: October 07, 2021

Single-cell transcriptomics identifies Mcl-1 as a target for senolytic therapy in cancer.

Single-cell transcriptomics identifies Mcl-1 as a target for senolytic therapy in cancer.

Journal: Nature communications

Published: July 16, 2021

Showing 1-12 of 19

Last Updated: 09/26/2026