Eminy H. Lee

TPQ, Taiwan

Last Updated: 09/26/2026

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Found 16 publications

APP SUMOylation prevents BACE1 cleavage of APP and increases BACE1 degradation to promote the nonamyloidogenic pathway.

APP SUMOylation prevents BACE1 cleavage of APP and increases BACE1 degradation to promote the nonamyloidogenic pathway.

Journal: Molecular medicine (Cambridge, Mass.)

Published: March 03, 2025

Novel role of NCoR1 in impairing spatial memory through the mediation of a novel interacting protein DEC2.

Novel role of NCoR1 in impairing spatial memory through the mediation of a novel interacting protein DEC2.

Journal: Cellular and molecular life sciences : CMLS

Published: February 10, 2024

Identification of Ndfip1 as a novel negative regulator for spatial memory formation associated with increased ubiquitination of Beclin 1 and PTEN.

Identification of Ndfip1 as a novel negative regulator for spatial memory formation associated with increased ubiquitination of Beclin 1 and PTEN.

Journal: PloS one

Published: October 11, 2022

Melatonin Induction of APP Intracellular Domain 50 SUMOylation Alleviates AD through Enhanced Transcriptional Activation and Aβ Degradation.

Melatonin Induction of APP Intracellular Domain 50 SUMOylation Alleviates AD through Enhanced Transcriptional Activation and Aβ Degradation.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: April 04, 2020

Restoring Wnt6 signaling ameliorates behavioral deficits in MeCP2 T158A mouse model of Rett syndrome.

Restoring Wnt6 signaling ameliorates behavioral deficits in MeCP2 T158A mouse model of Rett syndrome.

Journal: Scientific reports

Published: July 26, 2019

Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer's disease.

Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer's disease.

Journal: Cell death and differentiation

Published: October 01, 2018

Protein inhibitor of activated STAT1 Ser503 phosphorylation-mediated Elk-1 SUMOylation promotes neuronal survival in APP/PS1 mice.

Protein inhibitor of activated STAT1 Ser503 phosphorylation-mediated Elk-1 SUMOylation promotes neuronal survival in APP/PS1 mice.

Journal: British journal of pharmacology

Published: July 30, 2018

Smad4 SUMOylation is essential for memory formation through upregulation of the skeletal myopathy gene TPM2.

Smad4 SUMOylation is essential for memory formation through upregulation of the skeletal myopathy gene TPM2.

Journal: BMC biology

Published: June 18, 2017

Epigenetic regulation of HDAC1 SUMOylation as an endogenous neuroprotection against Aβ toxicity in a mouse model of Alzheimer's disease.

Epigenetic regulation of HDAC1 SUMOylation as an endogenous neuroprotection against Aβ toxicity in a mouse model of Alzheimer's disease.

Journal: Cell death and differentiation

Published: August 18, 2016

MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome.

MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome.

Journal: Nature communications

Published: August 26, 2015

CREB SUMOylation by the E3 ligase PIAS1 enhances spatial memory.

CREB SUMOylation by the E3 ligase PIAS1 enhances spatial memory.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience

Published: July 18, 2014

Hes-1 SUMOylation by protein inhibitor of activated STAT1 enhances the suppressing effect of Hes-1 on GADD45α expression to increase cell survival.

Hes-1 SUMOylation by protein inhibitor of activated STAT1 enhances the suppressing effect of Hes-1 on GADD45α expression to increase cell survival.

Journal: Journal of biomedical science

Published: April 01, 2014

Showing 1-12 of 16

Last Updated: 09/26/2026