Emir Sarduy-Salas

General San Martin, B, Argentina

Last Updated: 09/26/2026

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Found 24 publications

New hit compounds against Trypanosoma cruzi derived from mining yeast chemogenomic profiling data.

New hit compounds against Trypanosoma cruzi derived from mining yeast chemogenomic profiling data.

Journal: Antimicrobial agents and chemotherapy

Published: June 04, 2026

Purine derivatives as potential agents against Chagas disease: Ex vivo, in vitro, in silico evaluation, and identification of targets in Trypanosoma cruzi.

Purine derivatives as potential agents against Chagas disease: Ex vivo, in vitro, in silico evaluation, and identification of targets in Trypanosoma cruzi.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: April 20, 2026

Prioritization of chemical scaffolds using the TDR Targets database: An integrative workflow for Trypanosoma cruzi drug discovery.

Prioritization of chemical scaffolds using the TDR Targets database: An integrative workflow for Trypanosoma cruzi drug discovery.

Journal: PLoS neglected tropical diseases

Published: March 04, 2026

Identification of Antifungal Agents AR-12 and Fosmanogepix as Anti-Trypanosoma cruzi Drugs through an Enhanced Fluorogenic β-Galactosidase Phenotypic Screening Assay.

Identification of Antifungal Agents AR-12 and Fosmanogepix as Anti-Trypanosoma cruzi Drugs through an Enhanced Fluorogenic β-Galactosidase Phenotypic Screening Assay.

Journal: ACS infectious diseases

Published: January 02, 2026

Three Decades of Targeting Falcipains to Develop Antiplasmodial Agents: What have we Learned and What can be Done Next?

Three Decades of Targeting Falcipains to Develop Antiplasmodial Agents: What have we Learned and What can be Done Next?

Journal: Current medicinal chemistry

Published: March 28, 2023

Design, synthesis and biological evaluation of novel thiosemicarbazones as cruzipain inhibitors.

Design, synthesis and biological evaluation of novel thiosemicarbazones as cruzipain inhibitors.

Journal: European journal of medicinal chemistry

Published: January 30, 2023

Enzyme Inhibitors from Gorgonians and Soft Corals.

Enzyme Inhibitors from Gorgonians and Soft Corals.

Journal: Marine drugs

Published: December 23, 2022

The Trypanosoma cruzi Antigen and Epitope Atlas: antibody specificities in Chagas disease patients across the Americas.

The Trypanosoma cruzi Antigen and Epitope Atlas: antibody specificities in Chagas disease patients across the Americas.

Journal: Nature communications

Published: August 11, 2022

Thiosemicarbazone derivatives: Evaluation as cruzipain inhibitors and molecular modeling study of complexes with cruzain.

Thiosemicarbazone derivatives: Evaluation as cruzipain inhibitors and molecular modeling study of complexes with cruzain.

Journal: Bioorganic & medicinal chemistry

Published: January 14, 2022

Tetracycline Derivatives Inhibit Plasmodial Cysteine Protease Falcipain-2 through Binding to a Distal Allosteric Site.

Tetracycline Derivatives Inhibit Plasmodial Cysteine Protease Falcipain-2 through Binding to a Distal Allosteric Site.

Journal: Journal of chemical information and modeling

Published: December 28, 2021

In silico identification of noncompetitive inhibitors targeting an uncharacterized allosteric site of falcipain-2.

In silico identification of noncompetitive inhibitors targeting an uncharacterized allosteric site of falcipain-2.

Journal: Journal of computer-aided molecular design

Published: May 25, 2021

Screening and Identification of Metacaspase Inhibitors: Evaluation of Inhibition Mechanism and Trypanocidal Activity.

Screening and Identification of Metacaspase Inhibitors: Evaluation of Inhibition Mechanism and Trypanocidal Activity.

Journal: Antimicrobial agents and chemotherapy

Published: June 24, 2020

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Last Updated: 09/26/2026