Emma L. Clayton
London, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 16 publications
Beginning from the end: the presynaptic terminal as a pathomechanism hub in frontotemporal dementia and amyotrophic lateral sclerosis.
Journal: Neural regeneration research
Published: June 10, 2024
Synaptopathy: presynaptic convergence in frontotemporal dementia and amyotrophic lateral sclerosis.
Journal: Brain : a journal of neurology
Published: August 18, 2023
Synaptopathy in CHMP2B frontotemporal dementia highlights the synaptic vesicle cycle as a therapeutic target.
Journal: Neural regeneration research
Published: July 28, 2022
Synaptic tau: A pathological or physiological phenomenon?
Journal: Acta neuropathologica communications
Published: August 11, 2021
A novel synaptopathy-defective synaptic vesicle protein trafficking in the mutant CHMP2B mouse model of frontotemporal dementia.
Journal: Journal of neurochemistry
Published: March 31, 2021
The integration site of the APP transgene in the J20 mouse model of Alzheimer's disease.
Journal: Wellcome open research
Published: September 24, 2018
Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown.
Journal: Brain : a journal of neurology
Published: December 08, 2017
G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.
Journal: EMBO molecular medicine
Published: November 09, 2017
Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation.
Journal: Human molecular genetics
Published: September 16, 2016
Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology.
Journal: Acta neuropathologica
Published: July 07, 2015
Last Updated: 09/26/2026