Emmanuel Darcq

Montreal, QC, Canada

Last Updated: 09/26/2026

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Found 68 publications

Gut microbiota as a novel therapeutic target for eating disorders and obesity.

Gut microbiota as a novel therapeutic target for eating disorders and obesity.

Journal: British journal of pharmacology

Published: February 24, 2026

IFNγ-associated immune-metabolic remodeling is linked to serotonin-kynurenine imbalance and cortical vulnerability in lupus-prone mice.

IFNγ-associated immune-metabolic remodeling is linked to serotonin-kynurenine imbalance and cortical vulnerability in lupus-prone mice.

Journal: Frontiers in immunology

Published: November 05, 2025

The neural circuits and signalling pathways of opioid use disorder.

The neural circuits and signalling pathways of opioid use disorder.

Journal: Nature reviews. Neuroscience

Published: September 26, 2025

Incubation of social deficit during morphine abstinence in male mice using a novel unbiased and automatized method.

Incubation of social deficit during morphine abstinence in male mice using a novel unbiased and automatized method.

Journal: Frontiers in behavioral neuroscience

Published: September 02, 2025

Targeting Mu Opioid Receptor Neurons of the Habenula to Limit Naloxone Aversion.

Targeting Mu Opioid Receptor Neurons of the Habenula to Limit Naloxone Aversion.

Journal: Biological psychiatry

Published: September 01, 2025

The GPR88 Agonist RTI-122 Reduces Alcohol-Related Motivation and Consumption.

The GPR88 Agonist RTI-122 Reduces Alcohol-Related Motivation and Consumption.

Journal: Addiction biology

Published: February 21, 2025

Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for In Vivo Mouse Studies.

Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for In Vivo Mouse Studies.

Journal: Journal of medicinal chemistry

Published: July 01, 2024

Neuroscience and addiction research: current advances and perspectives.

Neuroscience and addiction research: current advances and perspectives.

Journal: Journal of neural transmission (Vienna, Austria : 1996)

Published: February 19, 2024

Model of negative affect induced by withdrawal from acute and chronic morphine administration in male mice.

Model of negative affect induced by withdrawal from acute and chronic morphine administration in male mice.

Journal: Scientific reports

Published: December 29, 2023

Chronic Morphine Leaves a Durable Fingerprint on Whole-Brain Functional Connectivity.

Chronic Morphine Leaves a Durable Fingerprint on Whole-Brain Functional Connectivity.

Journal: Biological psychiatry

Published: September 21, 2023

Chronic tianeptine induces tolerance in analgesia and hyperlocomotion via mu-opioid receptor activation in mice.

Chronic tianeptine induces tolerance in analgesia and hyperlocomotion via mu-opioid receptor activation in mice.

Journal: Frontiers in psychiatry

Published: March 14, 2023

Improvement of the Metabolic Stability of GPR88 Agonist RTI-13951-33: Design, Synthesis, and Biological Evaluation.

Improvement of the Metabolic Stability of GPR88 Agonist RTI-13951-33: Design, Synthesis, and Biological Evaluation.

Journal: Journal of medicinal chemistry

Published: February 07, 2023

Showing 1-12 of 68

Last Updated: 09/26/2026