Enrico Patrucco
Turin, Italy
Last Updated: 09/26/2026
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Found 18 publications
EML4-ALK mediates resistance to KRAS G12C inhibition and induces an oncogenic dependency by rewiring signaling through the wild-type RAS pathway.
Journal: Cancer discovery
Published: March 18, 2025
SOS1 inhibitor BI-3406 shows in vivo antitumor activity akin to genetic ablation and synergizes with a KRASG12D inhibitor in KRAS LUAD.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: March 12, 2025
Oncogenic mutant KRAS inhibition through oxidation at cysteine 118.
Journal: Molecular oncology
Published: June 09, 2024
Active thymus in adult with lung cancer: preliminary results from the Adult Thymic Project.
Journal: Updates in surgery
Published: May 24, 2024
RAS-ON inhibition overcomes clinical resistance to KRAS G12C-OFF covalent blockade.
Journal: Nature communications
Published: November 21, 2023
cGMP-dependent kinase 2, Na+/H+ exchanger NHE3, and PDZ-adaptor NHERF2 co-assemble in apical membrane microdomains.
Journal: Acta physiologica (Oxford, England)
Published: October 12, 2023
Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma.
Journal: Science translational medicine
Published: June 28, 2023
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy.
Journal: Nature
Published: June 28, 2023
Genomic Profiling Identifies Putative Pathogenic Alterations in NSCLC Brain Metastases.
Journal: JTO clinical and research reports
Published: November 07, 2022
ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer.
Journal: Nature cancer
Published: February 23, 2022
Comparative Analysis and Isoform-Specific Therapeutic Vulnerabilities of KRAS Mutations in Non-Small Cell Lung Cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: July 28, 2021
Last Updated: 09/26/2026