Eric Deneault

Health Products And Food Branch
Ottawa, ON, Canada

Last Updated: 09/26/2026

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Found 31 publications

Special Issue "Research in iPSC-Based Disease Models".

Special Issue "Research in iPSC-Based Disease Models".

Journal: International journal of molecular sciences
Published: May 11, 2026

LRRK2 kinase mediates increased GCase activity in microglia in response to IFNγ-induced proinflammatory stimulation.

LRRK2 kinase mediates increased GCase activity in microglia in response to IFNγ-induced proinflammatory stimulation.

Journal: NPJ Parkinson's disease
Published: October 10, 2025

Activation of endogenous PRKN by structural derepression is linked to increased turnover of the E3 ubiquitin ligase.

Activation of endogenous PRKN by structural derepression is linked to increased turnover of the E3 ubiquitin ligase.

Journal: Autophagy
Published: July 08, 2025

BMI1 represses G-quadruplex DNA formation to maintain genomic stability during replication.

BMI1 represses G-quadruplex DNA formation to maintain genomic stability during replication.

Journal: The Journal of biological chemistry
Published: June 12, 2025

Glucosylceramide-induced ectosomes propagate pathogenic α-synuclein in Parkinson's disease.

Glucosylceramide-induced ectosomes propagate pathogenic α-synuclein in Parkinson's disease.

Journal: Nature cell biology
Published: February 04, 2025

An X-linked long non-coding RNA, PTCHD1-AS, and the core features of autism.

An X-linked long non-coding RNA, PTCHD1-AS, and the core features of autism.

Journal: Nature
Published: December 10, 2024

An Inducible Luminescent System to Explore Parkinson's Disease-Associated Genes.

An Inducible Luminescent System to Explore Parkinson's Disease-Associated Genes.

Journal: International journal of molecular sciences
Published: June 30, 2024

Recent Therapeutic Gene Editing Applications to Genetic Disorders.

Recent Therapeutic Gene Editing Applications to Genetic Disorders.

Journal: Current issues in molecular biology
Published: March 31, 2024

Transcriptional Dysregulation and Impaired Neuronal Activity in FMR1 Knock-Out and Fragile X Patients' iPSC-Derived Models.

Transcriptional Dysregulation and Impaired Neuronal Activity in FMR1 Knock-Out and Fragile X Patients' iPSC-Derived Models.

Journal: International journal of molecular sciences
Published: August 31, 2023

Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons.

Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons.

Journal: iScience
Published: August 28, 2023

Canadian Regulatory Framework and Regulatory Requirements for Cell and Gene Therapy Products.

Canadian Regulatory Framework and Regulatory Requirements for Cell and Gene Therapy Products.

Journal: Advances in experimental medicine and biology
Published: August 01, 2023

Generation of patient-derived pluripotent stem cell-lines and CRISPR modified isogenic controls with mutations in the Parkinson's associated GBA gene.

Generation of patient-derived pluripotent stem cell-lines and CRISPR modified isogenic controls with mutations in the Parkinson's associated GBA gene.

Journal: Stem cell research
Published: July 07, 2022
Showing 1-12 of 31

Last Updated: 09/26/2026