Eric Destexhe

Rue De L'Institut 89
Rixensart, WAL 1330, Belgium

Last Updated: 09/26/2026

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Found 19 publications

A platform approach as a plausible option for nonclinical safety assessment of adjuvanted vaccines.

A platform approach as a plausible option for nonclinical safety assessment of adjuvanted vaccines.

Journal: NPJ vaccines

Published: April 04, 2025

Are Repeat-Dose Toxicity Studies Informative for Safety Assessment of Vaccine Candidates? A Survey of Vaccine Developers.

Are Repeat-Dose Toxicity Studies Informative for Safety Assessment of Vaccine Candidates? A Survey of Vaccine Developers.

Journal: International journal of toxicology

Published: October 30, 2024

Repeated-Dose Toxicity, Biodistribution, and Shedding Assessments With a ChAd155 Respiratory Syncytial Virus Vaccine Candidate Evaluated in Rabbits and Rats.

Repeated-Dose Toxicity, Biodistribution, and Shedding Assessments With a ChAd155 Respiratory Syncytial Virus Vaccine Candidate Evaluated in Rabbits and Rats.

Journal: International journal of toxicology

Published: June 02, 2022

Lack of effects on female fertility or pre- and postnatal development of offspring in rats after exposure to AS03-adjuvanted recombinant plant-derived virus-like particle vaccine candidate for COVID-19.

Lack of effects on female fertility or pre- and postnatal development of offspring in rats after exposure to AS03-adjuvanted recombinant plant-derived virus-like particle vaccine candidate for COVID-19.

Journal: Reproductive toxicology (Elmsford, N.Y.)

Published: August 30, 2021

Nonclinical safety assessment of repeated administration and biodistribution of ChAd3-EBO-Z Ebola candidate vaccine.

Nonclinical safety assessment of repeated administration and biodistribution of ChAd3-EBO-Z Ebola candidate vaccine.

Journal: Journal of applied toxicology : JAT

Published: October 14, 2019

Chimeric hemagglutinin supra-seasonal universal influenza vaccine candidates administered sequentially by the intramuscular route are locally and systemically well-tolerated in rabbits.

Chimeric hemagglutinin supra-seasonal universal influenza vaccine candidates administered sequentially by the intramuscular route are locally and systemically well-tolerated in rabbits.

Journal: Regulatory toxicology and pharmacology : RTP

Published: August 23, 2019

Oral Vaccination with Replication-Competent Adenovirus in Mice Reveals Dissemination of the Viral Vaccine beyond the Gastrointestinal Tract.

Oral Vaccination with Replication-Competent Adenovirus in Mice Reveals Dissemination of the Viral Vaccine beyond the Gastrointestinal Tract.

Journal: Journal of virology

Published: February 12, 2019

Signal management in pharmacovigilance and human risk assessment of CpG 7909, integrating embryo-fetal and post-natal developmental toxicity studies in rats and rabbits.

Signal management in pharmacovigilance and human risk assessment of CpG 7909, integrating embryo-fetal and post-natal developmental toxicity studies in rats and rabbits.

Journal: Reproductive toxicology (Elmsford, N.Y.)

Published: February 17, 2017

Evaluation of the potential effects of AS03-adjuvanted A(H1N1)pdm09 vaccine administration on the central nervous system of non-primed and A(H1N1)pdm09-primed cotton rats.

Evaluation of the potential effects of AS03-adjuvanted A(H1N1)pdm09 vaccine administration on the central nervous system of non-primed and A(H1N1)pdm09-primed cotton rats.

Journal: Human vaccines & immunotherapeutics

Published: September 16, 2016

Intramuscularly administered herpes zoster subunit vaccine has no effects on fertility, pre- and post-natal development in Sprague-Dawley rats.

Intramuscularly administered herpes zoster subunit vaccine has no effects on fertility, pre- and post-natal development in Sprague-Dawley rats.

Journal: Reproductive toxicology (Elmsford, N.Y.)

Published: June 16, 2016

Non-clinical safety assessment of single and repeated administration of gE/AS01 zoster vaccine in rabbits.

Non-clinical safety assessment of single and repeated administration of gE/AS01 zoster vaccine in rabbits.

Journal: Journal of applied toxicology : JAT

Published: November 19, 2015

Effects of Adjuvant Systems on the cardiovascular and respiratory functions in telemetered conscious dogs and anaesthetised rats.

Effects of Adjuvant Systems on the cardiovascular and respiratory functions in telemetered conscious dogs and anaesthetised rats.

Journal: Regulatory toxicology and pharmacology : RTP

Published: February 16, 2015

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Last Updated: 09/26/2026