Erika B. Villanueva
Vancouver, BC V5Z4H4, Canada
Last Updated: 09/26/2026
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Found 12 publications
Distinct and combined interferon-ɑ/β-receptor-1 loss in neurons and astrocytes disrupt brain energy metabolism and drive Parkinsonian dementia.
Journal: Journal of biomedical science
Published: August 21, 2025
Neuronal TNFα, Not α-Syn, Underlies PDD-Like Disease Progression in IFNβ-KO Mice.
Journal: Annals of neurology
Published: March 17, 2021
Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease.
Journal: Science translational medicine
Published: November 03, 2017
HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo.
Journal: Human molecular genetics
Published: August 22, 2017
A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles.
Journal: Human molecular genetics
Published: October 20, 2016
An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes.
Journal: Human molecular genetics
Published: April 01, 2016
Ultrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppression.
Journal: Scientific reports
Published: February 05, 2015
Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease.
Journal: Neurobiology of disease
Published: June 11, 2014
In vivo evaluation of candidate allele-specific mutant huntingtin gene silencing antisense oligonucleotides.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: April 16, 2014
Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS.
Journal: Nucleic acids research
Published: August 22, 2013
Mitochondrial transcription factor A (Tfam) is a pro-inflammatory extracellular signaling molecule recognized by brain microglia.
Journal: Molecular and cellular neurosciences
Published: July 15, 2013
A fully humanized transgenic mouse model of Huntington disease.
Journal: Human molecular genetics
Published: September 25, 2012
Showing 1-12 of 12
Last Updated: 09/26/2026