Last Updated: 09/26/2026
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Found 14 publications
A Bispecific Modeling Framework Enables the Prediction of Efficacy, Toxicity, and Optimal Molecular Design of Bispecific Antibodies Targeting MerTK.
Journal: The AAPS journal
Published: September 22, 2023
Tumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer.
Journal: Nature communications
Published: January 31, 2023
PEGylation of anti-MerTK Antibody Modulates Ocular Biodistribution.
Journal: Bioconjugate chemistry
Published: September 25, 2022
Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP.
Journal: Immunity
Published: June 25, 2019
MAP4K4 negatively regulates CD8 T cell-mediated antitumor and antiviral immunity.
Journal: Science immunology
Published: May 30, 2019
Autophagy Regulation of Metabolism Is Required for CD8+ T Cell Anti-tumor Immunity.
Journal: Cell reports
Published: March 06, 2018
Chemotherapy Combines Effectively with Anti-PD-L1 Treatment and Can Augment Antitumor Responses.
Journal: Journal of immunology (Baltimore, Md. : 1950)
Published: February 26, 2018
Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis.
Journal: ACS medicinal chemistry letters
Published: April 24, 2015
AXL inhibition sensitizes mesenchymal cancer cells to antimitotic drugs.
Journal: Cancer research
Published: August 16, 2014
Discovery of selective 4-Amino-pyridopyrimidine inhibitors of MAP4K4 using fragment-based lead identification and optimization.
Journal: Journal of medicinal chemistry
Published: March 29, 2014
Assessment of the hepatic CYP reductase null mouse model and its potential application in drug discovery.
Journal: Molecular pharmaceutics
Published: January 24, 2014
Last Updated: 09/26/2026