Esmee Koedoot

Leiden, ZH 2333CC, Netherlands

Last Updated: 09/26/2026

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Found 14 publications

Pharmacological CLK inhibition disrupts SR protein function and RNA splicing blocking cell growth and migration in TNBC.

Pharmacological CLK inhibition disrupts SR protein function and RNA splicing blocking cell growth and migration in TNBC.

Journal: Breast cancer research : BCR
Published: March 26, 2025

Ex vivo 3D micro-tumour testing platform for predicting clinical response to platinum-based therapy in patients with high-grade serous ovarian cancer.

Ex vivo 3D micro-tumour testing platform for predicting clinical response to platinum-based therapy in patients with high-grade serous ovarian cancer.

Journal: NPJ precision oncology
Published: January 03, 2025

Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response.

Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response.

Journal: Journal of experimental & clinical cancer research : CR
Published: December 20, 2023

A kinase inhibitor screen reveals MEK1/2 as a novel therapeutic target to antagonize IGF1R-mediated antiestrogen resistance in ERα-positive luminal breast cancer.

A kinase inhibitor screen reveals MEK1/2 as a novel therapeutic target to antagonize IGF1R-mediated antiestrogen resistance in ERα-positive luminal breast cancer.

Journal: Biochemical pharmacology
Published: June 10, 2022

Splicing factors control triple-negative breast cancer cell mitosis through SUN2 interaction and sororin intron retention.

Splicing factors control triple-negative breast cancer cell mitosis through SUN2 interaction and sororin intron retention.

Journal: Journal of experimental & clinical cancer research : CR
Published: October 29, 2020

Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy.

Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy.

Journal: Scientific reports
Published: October 03, 2020

Splicing regulatory factors in breast cancer hallmarks and disease progression.

Splicing regulatory factors in breast cancer hallmarks and disease progression.

Journal: Oncotarget
Published: April 23, 2019

Migration rather than proliferation transcriptomic signatures are strongly associated with breast cancer patient survival.

Migration rather than proliferation transcriptomic signatures are strongly associated with breast cancer patient survival.

Journal: Scientific reports
Published: February 15, 2019

Co-regulated gene expression of splicing factors as drivers of cancer progression.

Co-regulated gene expression of splicing factors as drivers of cancer progression.

Journal: Scientific reports
Published: August 31, 2018

Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes.

Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes.

Journal: Nature communications
Published: February 28, 2018

Comprehensive Landscape of Nrf2 and p53 Pathway Activation Dynamics by Oxidative Stress and DNA Damage.

Comprehensive Landscape of Nrf2 and p53 Pathway Activation Dynamics by Oxidative Stress and DNA Damage.

Journal: Chemical research in toxicology
Published: December 17, 2016

Alternative signaling network activation through different insulin receptor family members caused by pro-mitogenic antidiabetic insulin analogues in human mammary epithelial cells.

Alternative signaling network activation through different insulin receptor family members caused by pro-mitogenic antidiabetic insulin analogues in human mammary epithelial cells.

Journal: Breast cancer research : BCR
Published: January 29, 2015
Showing 1-12 of 14

Last Updated: 09/26/2026