Eugene Futai

Sendai, 9808572, Japan

Last Updated: 09/26/2026

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Found 17 publications

Saccharomyces cerevisiae Models of Alzheimer's Disease to Screen Genes, Mutations, and Chemicals Affecting Amyloid Beta Production by γ-Secretase.

Saccharomyces cerevisiae Models of Alzheimer's Disease to Screen Genes, Mutations, and Chemicals Affecting Amyloid Beta Production by γ-Secretase.

Journal: Journal of visualized experiments : JoVE
Published: July 14, 2025

Microcystis viridis NIES-102 Cyanobacteria Lectin (MVL) Interacts with SARS-CoV-2 Spike Protein Receptor Binding Domains (RBDs) via Protein-Protein Interaction.

Microcystis viridis NIES-102 Cyanobacteria Lectin (MVL) Interacts with SARS-CoV-2 Spike Protein Receptor Binding Domains (RBDs) via Protein-Protein Interaction.

Journal: International journal of molecular sciences
Published: May 23, 2024

C-terminal amino acids in the type I transmembrane domain of L-type lectin VIP36 affect γ-secretase susceptibility.

C-terminal amino acids in the type I transmembrane domain of L-type lectin VIP36 affect γ-secretase susceptibility.

Journal: Biochemical and biophysical research communications
Published: August 17, 2023

A Metalloproteinase Cocktail from the Venom of Protobothrops flavoviridis Cleaves Amyloid Beta Peptides at the α-Cleavage Site.

A Metalloproteinase Cocktail from the Venom of Protobothrops flavoviridis Cleaves Amyloid Beta Peptides at the α-Cleavage Site.

Journal: Toxins
Published: July 21, 2023

Specific Mutations near the Amyloid Precursor Protein Cleavage Site Increase γ-Secretase Sensitivity and Modulate Amyloid-β Production.

Specific Mutations near the Amyloid Precursor Protein Cleavage Site Increase γ-Secretase Sensitivity and Modulate Amyloid-β Production.

Journal: International journal of molecular sciences
Published: December 09, 2022

Specific Mutations in Aph1 Cause γ-Secretase Activation.

Specific Mutations in Aph1 Cause γ-Secretase Activation.

Journal: International journal of molecular sciences
Published: December 10, 2021

Focused Proteomics Analysis of Habu Snake (Protobothrops flavoviridis) Venom Using Antivenom-Based Affinity Chromatography Reveals Novel Myonecrosis-Enhancing Activity of Thrombin-Like Serine Proteases.

Focused Proteomics Analysis of Habu Snake (Protobothrops flavoviridis) Venom Using Antivenom-Based Affinity Chromatography Reveals Novel Myonecrosis-Enhancing Activity of Thrombin-Like Serine Proteases.

Journal: Frontiers in pharmacology
Published: August 29, 2021

Curcumin Derivative GT863 Inhibits Amyloid-Beta Production via Inhibition of Protein N-Glycosylation.

Curcumin Derivative GT863 Inhibits Amyloid-Beta Production via Inhibition of Protein N-Glycosylation.

Journal: Cells
Published: December 27, 2019

Advanced Yeast Models of Familial Alzheimer Disease Expressing FAD-Linked Presenilin to Screen Mutations and γ-Secretase Modulators.

Advanced Yeast Models of Familial Alzheimer Disease Expressing FAD-Linked Presenilin to Screen Mutations and γ-Secretase Modulators.

Journal: Methods in molecular biology (Clifton, N.J.)
Published: October 12, 2019

Specific mutations in presenilin 1 cause conformational changes in γ-secretase to modulate amyloid β trimming.

Specific mutations in presenilin 1 cause conformational changes in γ-secretase to modulate amyloid β trimming.

Journal: Journal of biochemistry
Published: September 04, 2017

Specific combinations of presenilins and Aph1s affect the substrate specificity and activity of γ-secretase.

Specific combinations of presenilins and Aph1s affect the substrate specificity and activity of γ-secretase.

Journal: Biochemical and biophysical research communications
Published: August 25, 2016

Functional properties of gamma-secretase in the yeast reconstitution system

Functional properties of gamma-secretase in the yeast reconstitution system

Journal: Seikagaku. The Journal of Japanese Biochemical Society
Published: May 20, 2016
Showing 1-12 of 17

Last Updated: 09/26/2026