Eunhwa Ko
R&D Center
Incheon, Republic of Korea
Incheon, Republic of Korea
Last Updated: 09/26/2026
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Found 10 publications
FRTX-02, a selective and potent inhibitor of DYRK1A, modulates inflammatory pathways in mouse models of psoriasis and atopic dermatitis.
Journal: Journal of translational autoimmunity
Published: October 05, 2022
X-ray Crystal Structure-Guided Design and Optimization of 7H-Pyrrolo[2,3-d]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor.
Journal: Journal of medicinal chemistry
Published: May 04, 2021
Brain injury induces HIF-1α-dependent transcriptional activation of LRRK2 that exacerbates brain damage.
Journal: Cell death & disease
Published: September 29, 2018
The small molecule CA140 inhibits the neuroinflammatory response in wild-type mice and a mouse model of AD.
Journal: Journal of neuroinflammation
Published: May 08, 2018
Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors.
Journal: Journal of medicinal chemistry
Published: August 18, 2017
Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation.
Journal: ACS chemical biology
Published: August 03, 2017
A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader.
Journal: Cell chemical biology
Published: May 30, 2017
Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL.
Journal: Angewandte Chemie (International ed. in English)
Published: August 14, 2015
Catalytic in vivo protein knockdown by small-molecule PROTACs.
Journal: Nature chemical biology
Published: May 08, 2015
Showing 1-10 of 10
Last Updated: 09/26/2026