Eva Mezeiova

Hradec Kralove, KR 50005, Czech Republic

Last Updated: 09/26/2026

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Found 31 publications

Balancing rigidity and flexibility: Optimised 4-(hexyloxy)benzoate antagonists with enhanced affinity and tuneable duration at muscarinic receptors.

Balancing rigidity and flexibility: Optimised 4-(hexyloxy)benzoate antagonists with enhanced affinity and tuneable duration at muscarinic receptors.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: July 29, 2025

Effect of hexyloxy position on antagonistic properties of KH-5 (1-{2-[4-(hexyloxy)benzoyloxy]ethyl}-1-methyl-1,2,3,6-tetrahydropyridin-1-ium iodide) at muscarinic acetylcholine receptors.

Effect of hexyloxy position on antagonistic properties of KH-5 (1-{2-[4-(hexyloxy)benzoyloxy]ethyl}-1-methyl-1,2,3,6-tetrahydropyridin-1-ium iodide) at muscarinic acetylcholine receptors.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: September 17, 2024

Morphing cholinesterase inhibitor amiridine into multipotent drugs for the treatment of Alzheimer's disease.

Morphing cholinesterase inhibitor amiridine into multipotent drugs for the treatment of Alzheimer's disease.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: December 27, 2023

2,6-Disubstituted 7-(naphthalen-2-ylmethyl)-7H-purines as a new class of potent antitubercular agents inhibiting DprE1.

2,6-Disubstituted 7-(naphthalen-2-ylmethyl)-7H-purines as a new class of potent antitubercular agents inhibiting DprE1.

Journal: European journal of medicinal chemistry

Published: May 04, 2023

Non-covalent acetylcholinesterase inhibitors: In vitro screening and molecular modeling for novel selective insecticides.

Non-covalent acetylcholinesterase inhibitors: In vitro screening and molecular modeling for novel selective insecticides.

Journal: Toxicology in vitro : an international journal published in association with BIBRA

Published: June 13, 2022

UHPLC-HRMS study of pharmacokinetics of a novel hybrid cholinesterase inhibitor K1234: A comparison between in silico, in vitro and in vivo data.

UHPLC-HRMS study of pharmacokinetics of a novel hybrid cholinesterase inhibitor K1234: A comparison between in silico, in vitro and in vivo data.

Journal: Journal of pharmaceutical and biomedical analysis

Published: April 06, 2022

Novel D2/5-HT receptor modulators related to cariprazine with potential implication to schizophrenia treatment.

Novel D2/5-HT receptor modulators related to cariprazine with potential implication to schizophrenia treatment.

Journal: European journal of medicinal chemistry

Published: January 03, 2022

Recent advances in dopamine D2 receptor ligands in the treatment of neuropsychiatric disorders.

Recent advances in dopamine D2 receptor ligands in the treatment of neuropsychiatric disorders.

Journal: Medicinal research reviews

Published: September 14, 2021

Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D2 3,4-dihydroquinolin-2(1H)-one Derivatives Related to Aripiprazole.

Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D2 3,4-dihydroquinolin-2(1H)-one Derivatives Related to Aripiprazole.

Journal: Biomolecules

Published: July 15, 2021

Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease.

Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease.

Journal: ACS chemical neuroscience

Published: April 14, 2021

Discovery of multifunctional anti-Alzheimer's agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters.

Discovery of multifunctional anti-Alzheimer's agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters.

Journal: European journal of medicinal chemistry

Published: February 26, 2021

Huprine Y - Tryptophan heterodimers with potential implication to Alzheimer's disease treatment.

Huprine Y - Tryptophan heterodimers with potential implication to Alzheimer's disease treatment.

Journal: Bioorganic & medicinal chemistry letters

Published: February 12, 2021

Showing 1-12 of 31

Last Updated: 09/26/2026